The Department of Cell and Developmental Biology at the University of Massachusetts Medical School is at the center of exciting new advances in understanding basic biological and biomedical processes to promote clinical and translational science. Research addresses the organization, assembly and activity of the regulatory machinery for cell growth and aging, differentiation and development, as well as genetic and epigenetic control of gene expression in human embryonic stem cells and lineage committed cells; with implications for treatment of cancers, bone diseases, reproductive disorders, genetic conditions and neurodegenerative and psychiatric disorders. This collection showcases the books, journal articles, book reviews, and other publications and presentations written by faculty and researchers of the Department of Cell and Developmental Biology.


Submissions from 2011

Link

Versatility of PRMT5-induced methylation in growth control and development, Vrajesh Karkhanis, Yu-Jie Hu, Robert A. Baiocchi, Anthony N. Imbalzano, and Said Sif (Trends in biochemical sciences)

Link

Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop, Sundeep Khosla, Teresita M. Bellido, Marc K. Drezner, Catherine M. Gordon, Tamara B. Harris, Douglas P. Kiel, Barbara E. Kream, Meryl S. LeBoff, Jane B. Lian, Charlotte A. Peterson, Clifford J. Rosen, John P. Williams, Karen K. Winer, and Sherry S. Sherman (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research)

Link

Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis, Jae-Sung Kim, Jeffrey S. Kroin, Asokumar Buvanendran, Xin Li, Andre J. Van Wijnen, Kenneth J. Tuman, and Hee-Jeong Im (Arthritis and rheumatism)

PDF

The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain, Jae-Sung Kim, Jeffrey S. Kroin, Xin Li, Howard S. An, Asokumar Buvanendran, Dongyao Yan, Kenneth J. Tuman, Andre J. Van Wijnen, Di Chen, and Hee-Jeong Im (Arthritis research and therapy)

PDF

Regulation of senescence in cancer and aging, Yahui Kong, Hang Cui, Charusheila Ramkumar, and Hong Zhang (Journal of Aging Research)

Link

Smurf2-mediated ubiquitination and degradation of Id1 regulates p16 expression during senescence, Yahui Kong, Hang Cui, and Hong Zhang (Aging cell)

PDF

Dioxin Exposure and Age of Pubertal Onset Among Russian Boys, Susan A. Korrick, Mary M. Lee, Paige L. Williams, Oleg Sergeyev, Jane S. Burns, Donald G. Patterson, Wayman E. Turner, Larry L. Needham, Larisa Altshul, Boris Revich, and Russ Hauser (Environmental health perspectives)

PDF

Repeated cleavage failure does not establish centrosome amplification in untransformed human cells, Anna Krzywicka-Racka and Greenfield Sluder (The Journal of cell biology)

Link

Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation, Julie C. Liu, Christopher Joachim Lengner, Tripti Gaur, Yang Lou, Sadiq Hussain, Marci D. Jones, Brent Borodic, Jennifer L. Colby, Heather Anne Steinman, Andre J. Van Wijnen, Janet L. Stein, Stephen N. Jones, Gary S. Stein, and Jane B. Lian (The Journal of biological chemistry)

Link

Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development, Lijun Liu, Ronglin Xie, Sadiq Hussain, Jane B. Lian, Jaime A. Rivera-Perez, Stephen N. Jones, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen (Gene)

Link

Tropomyosin position on F-actin revealed by EM reconstruction and computational chemistry, Xiachuan Edward Li, Larry S. Tobacman, Ji Young Mun, Roger W. Craig, Stefan Fischer, and William Lehman (Biophysical journal)

Link

MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis, Xin Li, Gary Gibson, Jae-Sung Kim, Jeffrey S. Kroin, Shunbin Xu, Andre J. Van Wijnen, and Hee-Jeong Im (Gene)

Link

Osteoarthritic tissues modulate functional properties of sensory neurons associated with symptomatic OA pain, Xin Li, Jae-Sung Kim, Andre J. Van Wijnen, and Hee-Jeong Im (Molecular biology reports)

PDF

A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processing, Steven W. Long, Jenny Y. Y. Ooi, Peter M. Yau, and Peter L. Jones (Bioscience reports)

PDF

Modulation of striated muscle contraction by binding of myosin binding protein C to actin, Pradeep K. Luther and Roger W. Craig (Bioarchitecture)

PDF

Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle, Pradeep K. Luther, Hanspeter Winkler, Kenneth Taylor, Maria E. Zoghbi, Roger W. Craig, Raul Padron, John M. Squire, and Jun Liu (Proceedings of the National Academy of Sciences of the United States of America)

PDF

The expression of myogenic microRNAs indirectly requires protein arginine methyltransferase (Prmt)5 but directly requires Prmt4, Chandrashekara Mallappa, Yu-Jie Hu, Priscilla Shamulailatpam, Sookil Tae, Said Sif, and Anthony N. Imbalzano (Nucleic acids research)

Link

Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway, Melissa M. Matzelle, Maxime A. Gallant, Keith W. Condon, Nicole Walsh, Catherine A. Manning, Gary S. Stein, Jane B. Lian, David B. Burr, and Ellen M. Gravallese (Arthritis and rheumatism)

Link

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts, Meghan E. McGee-Lawrence, Angela L. McCleary-Wheeler, Frank J. Secreto, David F. Razidlo, Minzhi Zhang, Bridget A. Stensgard, Xiaodong Li, Gary S. Stein, Jane B. Lian, and Jennifer J. Westendorf (Bone)

Link

The increased incidence of congenital hypothyroidism: fact or fancy, Marvin L. Mitchell, Ho-Wen Hsu, Inderneel Sahai, Stuart J. Brink, Rosalind S. Brown, Laurie E. Cohen, Roger B. Eaton, Mary M. Lee, Lynne L. Levitsky, Edward Reiter, Abdollah Sadeghi-Nejad, Leslie A. Soyka, Joseph I. Wolfsdorf, and Bradford L. Therrell (Clinical endocrinology)

Link

The increased incidence of congenital hypothyroidism: fact or fancy?, Marvin L. Mitchell, Ho-Wen Hsu, Inderneel Sahai, Stuart J. Brink, Laurie E. Cohen, Rosalind S. Brown, Roger B. Eaton, Mary M. Lee, Lynne L. Levitsky, Edward Reiter, Abdollah Sadeghi-Nejad, Leslie A. Soyka, Joseph I. Wolfsdorf, and Massachusetts Pediatric Endocrine Work Group (Clinical endocrinology)

PDF

The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing, Luis G. Morello, Patricia P. Coltri, Alexandre J.C. Quaresma, Fernando M. Simabuco, Tereza C.L. Sila, Guramrit Singh, Jeffrey A. Nickerson, Carla C. Oliveira, Melissa J. Moore, and Nilson I. T. Zanchin (PloS one)

Link

Dicer is required for the formation of white but not brown adipose tissue, Rajini R. Mudhasani, Vishwajeet Puri, Kathleen Hoover, Michael P. Czech, Anthony N. Imbalzano, and Stephen N. Jones (Journal of cellular physiology)

Link

Electron microscopy and 3D reconstruction of F-actin decorated with cardiac myosin-binding protein C (cMyBP-C), Ji Young Mun, James Gulick, Jeffrey Robbins, John L. Woodhead, William Lehman, and Roger W. Craig (Journal of molecular biology)

Link

Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression, Shirwin M. Pockwinse, Krishna P. Kota, Alexandre J. C. Quaresma, Anthony N. Imbalzano, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jeffrey A. Nickerson (Journal of cellular physiology)

Link

Metastatic bone disease: Role of transcription factors and future targets, Jitesh Pratap, Jane B. Lian, and Gary S. Stein (Bone)

PDF

A Non-Specific Effect Associated with Conditional Transgene Expression Based on Cre-loxP Strategy in Mice, Linghua Qiu, Jaime A. Rivera-Perez, and Zuoshang Xu (PloS one)

Link

Mice defective in p53 nuclear localization signal 1 exhibit exencephaly, Anouk Regeling, Heather L. Armata, Judith Gallant, Stephen N. Jones, and Hayla Karen Sluss (Transgenic research)

PDF

Genome Sequence of an Australian Kangaroo, Macropus Eugenii, Provides Insight into the Evolution of Mammalian Reproduction and Development, Marilyn B. Renfree, Anthony T. Papenfuss, Janine E. Deakin, James Lindsay, Thomas Heider, Katherine Belov, Willem Rens, Paul D. Waters, Elizabeth A. Pharo, Geoff Shaw, Emily S. W. Wong, Christophe M. Lefevre, Kevin R. Nicholas, Yoko Kuroki, Matthew J. Wakefield, Kyall R. Zenger, Chenwei Wang, Malcolm Ferguson-Smith, Frank W. Nicholas, Danielle Hickford, Hongshi Yu, Kirsty R. Short, Hannah V. Siddle, Stephen R. Frankenberg, Keng Yih Chew, Brandon R. Menzies, Jessica M. Stringer, Shunsuke Suzuki, Timothy A. Hore, Margaret L. Delbridge, Amir Mohammadi, Nanette Y. Schneider, Yanqiu Hu, William O'Hara, Shafagh Al Nadaf, Chen Wu, Zhi-Ping Feng, Benjamin G. Cocks, Jianghui Wang, Paul Flicek, Stephen M. J. Searle, Susan Fairley, Kathryn Beal, Javier Herrero, Dawn M. Carone, Yutaka Suzuki, Sumio Sugano, Atsushi Toyoda, Yoshiyuki Sakaki, Shinji Kondo, Yuichiro Nishida, Shoji Tatsumoto, Ion Mandiou, Arthur Hsu, Kaighin A. McColl, Benjamin Lansdell, George Weinstock, Elizabeth Kuczek, Annette McGrath, Peter Wilson, Artem Men, Mehlika Hazar-Rethinam, Allison Hall, John Davis, David Wood, Sarah Williams, Yogi Sundaravadanam, Donna M. Muzny, Shalini N. Jhangiani, Lora R. Lewis, Margaret B. Morgan, Geoffrey O. Okwuonu, San Juana Ruiz, Jireh Santibanez, Lynne Nazareth, Andrew Cree, Gerald Fowler, Christie L. Kovar, Huyen H. Dinh, Vandita Joshi, Chyn Jing, Fremiet Lara, Rebecca Thornton, Lei Chen, Jixin Deng, Yue Liu, Joshua Y. Shen, Xing-Zhi Song, Janette Edson, Carmen Troon, Daniel Thomas, Amber Stephens, Lankesha Yapa, Tanya Levchenko, Richard A. Gibbs, Desmond W. Cooper, Terence P. Speed, Asao Fujiyama, Jennifer A.M. Graves, Rachel J. O'Neill, Andrew J. Pask, Susan M. Forrest, and Kim C. Worley (Genome biology)

Link

Cell movements, signaling and establishment of epigenetic states in early mammalian development, Jaime A. Rivera-Perez (Journal of cellular physiology)

Link

Regulation and function of axon guidance and adhesion molecules during olfactory map formation, Gerald A. Schwarting and Timothy R. Henion (Journal of cellular biochemistry)

Link

The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis, Stefania Senger, John Csokmay, Tanveer Akbar, Takako I. Jones, Prabuddha Sengupta, and Mary A Lilly (Development (Cambridge, England))

Link

An architectural genetic and epigenetic perspective, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Sayyed K. Zaidi, Jeffrey A. Nickerson, Martin A. Montecino, and Daniel W. Young (Integrative biology : quantitative biosciences from nano to macro)

Link

Mentoring fathers of children newly diagnosed with T1DM, Susan L. Sullivan-Bolyai, Carol Ann Bova, Mary M. Lee, and Philip Gruppuso (MCN. The American journal of maternal child nursing)

Link

Parent mentor perspectives on providing social support to empower parents, Susan Sullivan-Bolyai and Mary M. Lee (The Diabetes educator)

Link

Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein, Chia-Yun Jessica Sun, Silvana van Koningsbruggen, Steven W. Long, Kirsten Straasheijm, Rinse Klooster, Takako I. Jones, Michel Bellini, Lyne Levesque, William M. Brieher, Silvere M. van der Maarel, and Peter L. Jones (Journal of molecular biology)

Link

Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation, Yan Wang, Lei Gao, Christopher G. Conrad, and Athena Andreadis (Journal of cellular biochemistry)

Link

An SRp75/hnRNPG Complex Interacting with hnRNPE2 Regulates the 5' Splice Site of Tau Exon 10, Whose Misregulation Causes Frontotemporal Dementia, Yan Wang, Junning Wang, Lei Gao, Stefan Stamm, and Athena Andreadis (Gene)

Link

Chromatin accessibility and transcription factor binding at the PPARgamma2 promoter during adipogenesis is protein kinase a-dependent, Hengyi Xiao, Scott E. LeBlanc, Qiong Wu, Silvana Konda, Nunciada Salma, Concetta G. A. Marfella, Yasuyuki Ohkawa, and Anthony N. Imbalzano (Journal of cellular physiology)

Link

Cytocompatible poly(ethylene glycol)-co-polycarbonate hydrogels cross-linked by copper-free, strain-promoted click chemistry, Jianwen Xu, Tera M. Filion Potts, Fioleda Prifti, and Jie Song (Chemistry, an Asian journal)

PDF

Fibroblast Growth Factor Receptor 1 is Principally Responsible for Fibroblast Growth factor 2-induced catabolic activities in human articular chondrocytes, Gongyao Yan, Di Chen, Simon M. Cool, Andre J. Van Wijnen, Katalin Mikecz, Gillian Murphy, and Hee-Jeong Im (Arthritis research and therapy)

PDF

Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50, Yong Yang, Deborah A. Cochran, Mary D. Gargano, Iryna King, Nayef K. Samhat, Benjain P. Burger, Katherine R. Sabourin, Yuqing Hou, Junya Awata, David A.D. Parry, Wallace F. Marshall, George B. Witman, and Xiangyi Lu (Molecular biology of the cell)

Link

Bookmarking the genome: maintenance of epigenetic information, Sayyed K. Zaidi, Daniel W. Young, Martin A. Montecino, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, and Gary S. Stein (The Journal of biological chemistry)

Link

A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2, Ying Zhang, Ronglin Xie, Carlo M. Croce, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

Submissions from 2010

Link

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions, Jacqueline Akech, John J. Wixted, Krystin Bedard, Margaretha Van der Deen, Sadiq Hussain, T. A. Guise, Andre J. Van Wijnen, Janet L. Stein, Lucia R. Languino, Dario C. Altieri, Jitesh Pratap, E. Keller, Gary S. Stein, and Jane B. Lian (Oncogene)

Link

Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes, Syed A. Ali, Sayyed K. Zaidi, James G. Dobson Jr., A. Rauf Shakoori, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Proceedings of the National Academy of Sciences of the United States of America)

Link

The tempting illusion of genetic virtue, Athena Andreadis (Politics and the life sciences : the journal of the Association for Politics and the Life Sciences)

Link

MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival, Maria Pia Arrate, Tiffaney Vincent, Jessica Odvody, Rekha Kar, Stephen N. Jones, and Christine M. Eischen (Cancer research)

Link

Recruitment and subnuclear distribution of the regulatory machinery during 1alpha,25-dihydroxy vitamin D3-mediated transcriptional upregulation in osteoblasts, Gloria Arriagada, Berta Henriquez, Daniel Moena, Paola Merino, Cinthya Ruiz-Tagle, Jane B. Lian, Gary S. Stein, Janet L. Stein, and Martin A. Montecino (The Journal of steroid biochemistry and molecular biology)

Link

1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA, Gloria Arriagada, Roberto Paredes, Andre J. Van Wijnen, Jane B. Lian, Brigitte van Zundert, Gary S. Stein, Janet L. Stein, and Martin A. Montecino (Journal of cellular physiology)

Link

The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes, Rachit Bakshi, Mohammad Q. Hassan, Jitesh Pratap, Jane B. Lian, Martin A. Montecino, Andre J. Van Wijnen, Janet L. Stein, Anthony N. Imbalzano, and Gary S. Stein (Journal of cellular physiology)

Link

Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells, Klaus A. Becker, Prachi N. Ghule, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular physiology)

Link

Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming, Klaus A. Becker, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular physiology)

Link

DARPP-32 binds to tra2-beta1 and influences alternative splicing, Natalya Benderska, Kristina Becker, Jean-Antoine Girault, Cord-Michael Becker, Athena Andreadis, and Stefan Stamm (Biochimica et biophysica acta)

Link

Using osteoclast differentiation as a model for gene discovery in an undergraduate cell biology laboratory, Mark J. Birnbaum, Jenna Picco, Meghan Clements, Hanna Witwicka, Meilheng Yang, Margaret T. Hoey, and Paul R. Odgren (Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology)

Link

International stem cell registries, Joeri Borstlap, Mai X. Luong, Heather M. Rooke, B. Aran, A. Damaschun, A. Elstner, Kelly P. Smith, Gary S. Stein, and Anna Viega (In vitro cellular and developmental biology. Animal)

Link

Electron microscopy and three-dimensional reconstruction of native thin filaments reveal species-specific differences in regulatory strand densities, Anthony Cammarato, Roger W. Craig, and William Lehman (Biochemical and biophysical research communications)

Link

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells, Nathalie Cohet, Kathleen M. Stewart, Rajini R. Mudhasani, Ananthi J. Asirvatham, Chandrashekara Mallappa, Karen M. Imbalzano, Valerie M. Weaver, Anthony N. Imbalzano, and Jeffrey A. Nickerson (Journal of cellular physiology)

Link

Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity, Andrew H. Coles, Hugh S. Gannon, Anna M. Cerny, Evelyn A. Kurt-Jones, and Stephen N. Jones (Proceedings of the National Academy of Sciences of the United States of America)

PDF

CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content, Branch Craige, Che-Chia Tsao, Dennis R. Diener, Yuqing Hou, Karl-Ferdinand Lechtreck, Joel L. Rosenbaum, and George B. Witman (The Journal of cell biology)

Link

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation, Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Sayyed K. Zaidi, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Human molecular genetics)

Link

Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus, Hariharan P. Easwaran, Leander Van Neste, Leslie Cope, Subhojit Sen, Helai P. Mohammad, Gayle Jeannette Pageau, Jeanne B. Lawrence, James G. Herman, Kornel E. Schuebel, and Stephen B. Baylin (Cancer research)

Link

The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility, Zhiyou Fang, Norio Takizawa, Korey A. Wilson, Tara C. Smith, Anna M. Delprato, Michael W. Davidson, David G. Lambright, and Elizabeth J. Luna (Traffic (Copenhagen, Denmark))

Link

Shedding light on sperm pHertility, Harvey M. Florman, Melissa K. Jungnickel, and Keith A. Sutton (Cell)

Link

The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments, Agnieszka Galinska, Victoria Hatch, Roger W. Craig, Anne M. Murphy, Jennifer E. Van Eyk, C. L. Albert Wang, William Lehman, and D. Brian Foster (Circulation research)

Link

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse, Tripti Gaur, Sadiq Hussain, Rajini R. Mudhasani, Isha Parulkar, Jennifer L. Colby, Dana Frederick, Barbara E. Kream, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Stephen N. Jones, and Jane B. Lian (Developmental biology)

Link

Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1, Hira Lal Goel, Jean M. Underwood, Jeffrey A. Nickerson, Chung-Cheng Hsieh, and Lucia R. Languino (Journal of cellular physiology)

PDF

Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors, Jonathan A. R. Gordon, Mohammad Q. Hassan, Sharanjot Saini, Martin A. Montecino, Andre J. Van Wijnen, Gary S. Stein, Janet L. Stein, and Jane B. Lian (Molecular and cellular biology)

Link

Pregnancy modulates precursor cell proliferation in a murine model of focal demyelination, Shirin Haddady, Hoi Pang Low, Susan Billings-Gagliardi, Peter N. Riskind, and William J. Schwartz (Neuroscience)

Link

The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta, Min-Su Han, Hyo-Jin Kim, Hee-Jun Wee, Kyung-Eun Lim, Na-Rae Park, Suk-Chul Bae, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein, and Je-Yong Choi (Journal of cellular biochemistry)

Link

Infant formula, autoimmune triggers, and type 1 diabetes, David Harlan and Mary M. Lee (The New England journal of medicine)

Link

A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program, Mohammad Q. Hassan, Jonathan A. R. Gordon, Marcio M. Beloti, Carlo M. Croce, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Proceedings of the National Academy of Sciences of the United States of America)

Link

Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets, Mohammad Q. Hassan, Jonathan A. R. Gordon, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Journal of cellular biochemistry)

Link

Predictors of serum dioxin, furan, and PCB concentrations among women from Chapaevsk, Russia, Olivier Humblet, Paige L. Williams, Susan A. Korrick, Oleg Sergeyev, Claude Emond, Linda S. Birnbaum, Jane S. Burns, Larisa Altshul, Donald G. Patterson Jr., Wayman E. Turner, Mary M. Lee, Boris Revich, and Russ Hauser (Environmental science and technology)

PDF

The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues, Jae-Hwan Jeong, Youn-Kwan Jung, Hyo-Jin Kim, Jung-Sook Jin, Hyun-Nam Kim, Sang-Min Kang, Shin-Yoon Kim, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein, Shigeaki Kato, and Je-Yong Choi (Molecular and cellular biology)

Link

A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes, Marci D. Jones, Julie C. Liu, Thomas K. Barthel, Sadiq Hussain, Erik Lovria, Dengfeng Cheng, Jesse A. Schoonmaker, Sudhanshu Mulay, David C. Ayers, Mary L. Bouxsein, Gary S. Stein, Siddhartha Mukherjee, and Jane B. Lian (Clinical cancer research : an official journal of the American Association for Cancer Research)

Link

Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer, Byoung H. Kang, Markus D. Siegelin, Janet Plescia, Christopher M. Raskett, David S. Garlick, Takehiko Dohi, Jane B. Lian, Gary S. Stein, Lucia R. Languino, and Dario C. Altieri (Clinical cancer research : an official journal of the American Association for Cancer Research)

Link

CPEB4 is a cell survival protein retained in the nucleus upon ischemia or endoplasmic reticulum calcium depletion, Ming-Chung Kan, Aparna Oruganty-Das, Amalene Cooper-Morgan, Guang Jin, Sharon A. Swanger, Gary J. Bassell, Harvey M. Florman, Klaus van Leyen, and Joel D. Richter (Molecular and cellular biology)

Link

Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression, Kyle C. Kurek, Sara Del Mare, Zaidoun Salah, Suhaib Abdeen, Hussain Sadiq, Suk Hee Lee, Eugenio Gaudio, Nicola Zanesi, Kevin B. Jones, Barry DeYoung, Gail Amir, Mark Gebhardt, Matthew Warman, Gary S. Stein, Janet L. Stein, Jane B. Lian, and Rami I. Aqeilan (Cancer research)

PDF

Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility, David T. Leong, Jitesh Pratap, Barry P. Pereira, Saminathan S. Nathan, Jason R. Dobson, Jane B. Lian, Yoshiaki Ito, Gary S. Stein, Manuel Salto-Tellez, Simon M. Cool, Andre J. Van Wijnen, Joleen Lim, Xuewei Goh, Hui S. Kwok, and P. Mathijs Voorhoeve (Breast cancer research : BCR)

Link

Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway, Ling Ling, Christian Dombrowski, Kin Mun Foong, Larisa M. Haupt, Gary S. Stein, Victor Nurcombe, Andre J. Van Wijnen, and Simon M. Cool (The Journal of biological chemistry)

Link

Glycosaminoglycans modulate RANKL-induced osteoclastogenesis, Ling Ling, Sadasivam Murali, Gary S. Stein, Andre J. Van Wijnen, and Simon M. Cool (Journal of cellular biochemistry)

Link

Facioscapulohumeral muscular dystrophy region gene-1 (FRG-1) is an actin-bundling protein associated with muscle-attachment sites, Qian Liu, Takako I. Jones, Vivian W. Tang, William M. Brieher, and Peter L. Jones (Journal of cell science)

Link

Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function, Chandrashekara Mallappa, Brian T. Nasipak, Letitiah Etheridge, Elliot J. Androphy, Stephen N. Jones, Charles G. Sagerstrom, Yasuyuki Ohkawa, and Anthony N. Imbalzano (Molecular and cellular biology)

Link

Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl, Emily F. Mason, Yuxing Zhao, Pankuri Goraksha-Hicks, Jonathan L. Coloff, Hugh S. Gannon, Stephen N. Jones, and Jeffrey C. Rathmell (Cancer research)

Link

Cdk5 Regulates the Ubiquitination of PSD-95 in Neurons, Maria A. Morabito and Michael Bianchetta (Society for Neuroscience's 2010 Annual Meeting)

Link

An essential role for Dicer in adipocyte differentiation, Rajini R. Mudhasani, Anthony N. Imbalzano, and Stephen N. Jones (Journal of cellular biochemistry)

PDF

Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies, Paul R. Odgren, Craig H. Pratt, Carole A. MacKay, April Mason-Savas, Michelle Curtain, Lindsay S. Shopland, Tsutomu Ichicki, John P. Sundberg, and Leah Rae Donahue (PloS one)

Link

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss, Jitesh Pratap, Jacqueline Akech, John J. Wixted, Gabriela Szabo, Sadiq Hussain, Meghan E. McGee-Lawrence, Xiaodong Li, Krystin Bedard, Robinder J. Dhillon, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Jennifer J. Westendorf, and Jane B. Lian (Molecular cancer therapeutics)

Link

Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis, Meng Qiao, Yaqi Wang, Xiaoen Xu, Jing Lu, Yougli Dong, Wufan Tao, Janet L. Stein, Gary S. Stein, James D. Iglehart, Qian Shi, and Arthur B. Pardee (Molecular cell)

Link

Culture of whole mouse embryos at early postimplantation to organogenesis stages: developmental staging and methods, Jaime A. Rivera-PĂ©rez, Vanessa Jones, and Patrick P. L. Tam (Methods in enzymology)

Link

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice, JongDae Shin, Michael Bossenz, Young Chung, Hong Ma, Meg Byron, Naoko Taniguchi-Ishigaki, Xiaochun Zhu, Jiao Baowei, Lisa L. Hall, Michael R. Green, Stephen N. Jones, Irm Hermans-Borgmeyer, Jeanne B. Lawrence, and Ingolf Bach (Nature)

Link

Centriole duplication: analogue control in a digital age, Greenfield Sluder and Alexey Khodjakov (Cell biology international)

Link

Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis, Hayla Karen Sluss, Hugh S. Gannon, Andrew H. Coles, Qichang Shen, Christine M. Eischen, and Stephen N. Jones (Molecular cancer research : MCR)

Link

Novel interactors and a role for supervillin in early cytokinesis, Tara C. Smith, Zhiyou Fang, and Elizabeth J. Luna (Cytoskeleton (Hoboken, N.J.))

Link

Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, Sayyed K. Zaidi, and Daniel W. Young (Advances in enzyme regulation)

Link

Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments, Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Sayyed K. Zaidi, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein (Critical reviews in eukaryotic gene expression)

Link

Social Support to Empower Parents (STEP): an intervention for parents of young children newly diagnosed with type 1 diabetes, Susan Sullivan-Bolyai, Carol A. Bova, Katherine Leung, Allison Trudeau, Mary M. Lee, and Philip Gruppuso (The Diabetes educator)

Link

Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis, Yumi Uetake and Greenfield Sluder (Current biology : CB)

Link

The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells, Margaretha Van der Deen, Jacqueline Akech, Tao Wang, Thomas J. Fitzgerald, Dario C. Altieri, Lucia R. Languino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Journal of cellular biochemistry)