The Department of Cell and Developmental Biology at the University of Massachusetts Medical School is at the center of exciting new advances in understanding basic biological and biomedical processes to promote clinical and translational science. Research addresses the organization, assembly and activity of the regulatory machinery for cell growth and aging, differentiation and development, as well as genetic and epigenetic control of gene expression in human embryonic stem cells and lineage committed cells; with implications for treatment of cancers, bone diseases, reproductive disorders, genetic conditions and neurodegenerative and psychiatric disorders. This collection showcases the books, journal articles, book reviews, and other publications and presentations written by faculty and researchers of the Department of Cell and Developmental Biology.

Submissions from 2010

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Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming, Klaus A. Becker, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular physiology)

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DARPP-32 binds to tra2-beta1 and influences alternative splicing, Natalya Benderska, Kristina Becker, Jean-Antoine Girault, Cord-Michael Becker, Athena Andreadis, and Stefan Stamm (Biochimica et biophysica acta)

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Using osteoclast differentiation as a model for gene discovery in an undergraduate cell biology laboratory, Mark J. Birnbaum, Jenna Picco, Meghan Clements, Hanna Witwicka, Meilheng Yang, Margaret T. Hoey, and Paul R. Odgren (Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology)

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International stem cell registries, Joeri Borstlap, Mai X. Luong, Heather M. Rooke, B. Aran, A. Damaschun, A. Elstner, Kelly P. Smith, Gary S. Stein, and Anna Viega (In vitro cellular and developmental biology. Animal)

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Electron microscopy and three-dimensional reconstruction of native thin filaments reveal species-specific differences in regulatory strand densities, Anthony Cammarato, Roger W. Craig, and William Lehman (Biochemical and biophysical research communications)

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SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells, Nathalie Cohet, Kathleen M. Stewart, Rajini R. Mudhasani, Ananthi J. Asirvatham, Chandrashekara Mallappa, Karen M. Imbalzano, Valerie M. Weaver, Anthony N. Imbalzano, and Jeffrey A. Nickerson (Journal of cellular physiology)

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Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity, Andrew H. Coles, Hugh S. Gannon, Anna M. Cerny, Evelyn A. Kurt-Jones, and Stephen N. Jones (Proceedings of the National Academy of Sciences of the United States of America)

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CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content, Branch Craige, Che-Chia Tsao, Dennis R. Diener, Yuqing Hou, Karl-Ferdinand Lechtreck, Joel L. Rosenbaum, and George B. Witman (The Journal of cell biology)

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Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation, Christopher R. Dowdy, Ronglin Xie, Dana Frederick, Sadiq Hussain, Sayyed K. Zaidi, Diana Vradii, Amjad Javed, Xiangen Li, Stephen N. Jones, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Human molecular genetics)

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Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus, Hariharan P. Easwaran, Leander Van Neste, Leslie Cope, Subhojit Sen, Helai P. Mohammad, Gayle Jeannette Pageau, Jeanne B. Lawrence, James G. Herman, Kornel E. Schuebel, and Stephen B. Baylin (Cancer research)

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The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility, Zhiyou Fang, Norio Takizawa, Korey A. Wilson, Tara C. Smith, Anna M. Delprato, Michael W. Davidson, David G. Lambright, and Elizabeth J. Luna (Traffic (Copenhagen, Denmark))

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Shedding light on sperm pHertility, Harvey M. Florman, Melissa K. Jungnickel, and Keith A. Sutton (Cell)

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The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments, Agnieszka Galinska, Victoria Hatch, Roger W. Craig, Anne M. Murphy, Jennifer E. Van Eyk, C. L. Albert Wang, William Lehman, and D. Brian Foster (Circulation research)

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Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse, Tripti Gaur, Sadiq Hussain, Rajini R. Mudhasani, Isha Parulkar, Jennifer L. Colby, Dana Frederick, Barbara E. Kream, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Stephen N. Jones, and Jane B. Lian (Developmental biology)

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Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1, Hira Lal Goel, Jean M. Underwood, Jeffrey A. Nickerson, Chung-Cheng Hsieh, and Lucia R. Languino (Journal of cellular physiology)

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Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors, Jonathan A. R. Gordon, Mohammad Q. Hassan, Sharanjot Saini, Martin A. Montecino, Andre J. Van Wijnen, Gary S. Stein, Janet L. Stein, and Jane B. Lian (Molecular and cellular biology)

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Pregnancy modulates precursor cell proliferation in a murine model of focal demyelination, Shirin Haddady, Hoi Pang Low, Susan Billings-Gagliardi, Peter N. Riskind, and William J. Schwartz (Neuroscience)

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The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta, Min-Su Han, Hyo-Jin Kim, Hee-Jun Wee, Kyung-Eun Lim, Na-Rae Park, Suk-Chul Bae, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein, and Je-Yong Choi (Journal of cellular biochemistry)

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Infant formula, autoimmune triggers, and type 1 diabetes, David Harlan and Mary M. Lee (The New England journal of medicine)

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A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program, Mohammad Q. Hassan, Jonathan A. R. Gordon, Marcio M. Beloti, Carlo M. Croce, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (Proceedings of the National Academy of Sciences of the United States of America)

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Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets, Mohammad Q. Hassan, Jonathan A. R. Gordon, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Journal of cellular biochemistry)

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Predictors of serum dioxin, furan, and PCB concentrations among women from Chapaevsk, Russia, Olivier Humblet, Paige L. Williams, Susan A. Korrick, Oleg Sergeyev, Claude Emond, Linda S. Birnbaum, Jane S. Burns, Larisa Altshul, Donald G. Patterson Jr., Wayman E. Turner, Mary M. Lee, Boris Revich, and Russ Hauser (Environmental science and technology)

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The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues, Jae-Hwan Jeong, Youn-Kwan Jung, Hyo-Jin Kim, Jung-Sook Jin, Hyun-Nam Kim, Sang-Min Kang, Shin-Yoon Kim, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein, Shigeaki Kato, and Je-Yong Choi (Molecular and cellular biology)

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A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes, Marci D. Jones, Julie C. Liu, Thomas K. Barthel, Sadiq Hussain, Erik Lovria, Dengfeng Cheng, Jesse A. Schoonmaker, Sudhanshu Mulay, David C. Ayers, Mary L. Bouxsein, Gary S. Stein, Siddhartha Mukherjee, and Jane B. Lian (Clinical cancer research : an official journal of the American Association for Cancer Research)

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Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer, Byoung H. Kang, Markus D. Siegelin, Janet Plescia, Christopher M. Raskett, David S. Garlick, Takehiko Dohi, Jane B. Lian, Gary S. Stein, Lucia R. Languino, and Dario C. Altieri (Clinical cancer research : an official journal of the American Association for Cancer Research)

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CPEB4 is a cell survival protein retained in the nucleus upon ischemia or endoplasmic reticulum calcium depletion, Ming-Chung Kan, Aparna Oruganty-Das, Amalene Cooper-Morgan, Guang Jin, Sharon A. Swanger, Gary J. Bassell, Harvey M. Florman, Klaus van Leyen, and Joel D. Richter (Molecular and cellular biology)

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Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression, Kyle C. Kurek, Sara Del Mare, Zaidoun Salah, Suhaib Abdeen, Hussain Sadiq, Suk Hee Lee, Eugenio Gaudio, Nicola Zanesi, Kevin B. Jones, Barry DeYoung, Gail Amir, Mark Gebhardt, Matthew Warman, Gary S. Stein, Janet L. Stein, Jane B. Lian, and Rami I. Aqeilan (Cancer research)

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Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility, David T. Leong, Jitesh Pratap, Barry P. Pereira, Saminathan S. Nathan, Jason R. Dobson, Jane B. Lian, Yoshiaki Ito, Gary S. Stein, Manuel Salto-Tellez, Simon M. Cool, Andre J. Van Wijnen, Joleen Lim, Xuewei Goh, Hui S. Kwok, and P. Mathijs Voorhoeve (Breast cancer research : BCR)

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Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway, Ling Ling, Christian Dombrowski, Kin Mun Foong, Larisa M. Haupt, Gary S. Stein, Victor Nurcombe, Andre J. Van Wijnen, and Simon M. Cool (The Journal of biological chemistry)

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Glycosaminoglycans modulate RANKL-induced osteoclastogenesis, Ling Ling, Sadasivam Murali, Gary S. Stein, Andre J. Van Wijnen, and Simon M. Cool (Journal of cellular biochemistry)

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Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function, Chandrashekara Mallappa, Brian T. Nasipak, Letitiah Etheridge, Elliot J. Androphy, Stephen N. Jones, Charles G. Sagerstrom, Yasuyuki Ohkawa, and Anthony N. Imbalzano (Molecular and cellular biology)

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Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl, Emily F. Mason, Yuxing Zhao, Pankuri Goraksha-Hicks, Jonathan L. Coloff, Hugh S. Gannon, Stephen N. Jones, and Jeffrey C. Rathmell (Cancer research)

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Cdk5 Regulates the Ubiquitination of PSD-95 in Neurons, Maria A. Morabito and Michael Bianchetta (Society for Neuroscience's 2010 Annual Meeting)

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An essential role for Dicer in adipocyte differentiation, Rajini R. Mudhasani, Anthony N. Imbalzano, and Stephen N. Jones (Journal of cellular biochemistry)

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Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies, Paul R. Odgren, Craig H. Pratt, Carole A. MacKay, April Mason-Savas, Michelle Curtain, Lindsay S. Shopland, Tsutomu Ichicki, John P. Sundberg, and Leah Rae Donahue (PloS one)

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The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss, Jitesh Pratap, Jacqueline Akech, John J. Wixted, Gabriela Szabo, Sadiq Hussain, Meghan E. McGee-Lawrence, Xiaodong Li, Krystin Bedard, Robinder J. Dhillon, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Jennifer J. Westendorf, and Jane B. Lian (Molecular cancer therapeutics)

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Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis, Meng Qiao, Yaqi Wang, Xiaoen Xu, Jing Lu, Yougli Dong, Wufan Tao, Janet L. Stein, Gary S. Stein, James D. Iglehart, Qian Shi, and Arthur B. Pardee (Molecular cell)

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Culture of whole mouse embryos at early postimplantation to organogenesis stages: developmental staging and methods, Jaime A. Rivera-Pérez, Vanessa Jones, and Patrick P. L. Tam (Methods in enzymology)

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Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice, JongDae Shin, Michael Bossenz, Young Chung, Hong Ma, Meg Byron, Naoko Taniguchi-Ishigaki, Xiaochun Zhu, Jiao Baowei, Lisa L. Hall, Michael R. Green, Stephen N. Jones, Irm Hermans-Borgmeyer, Jeanne B. Lawrence, and Ingolf Bach (Nature)

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Centriole duplication: analogue control in a digital age, Greenfield Sluder and Alexey Khodjakov (Cell biology international)

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Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis, Hayla Karen Sluss, Hugh S. Gannon, Andrew H. Coles, Qichang Shen, Christine M. Eischen, and Stephen N. Jones (Molecular cancer research : MCR)

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Novel interactors and a role for supervillin in early cytokinesis, Tara C. Smith, Zhiyou Fang, and Elizabeth J. Luna (Cytoskeleton (Hoboken, N.J.))

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Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Carlo M. Croce, Je-Yong Choi, Syed A. Ali, Sandhya Pande, Mohammad Q. Hassan, Sayyed K. Zaidi, and Daniel W. Young (Advances in enzyme regulation)

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Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments, Gary S. Stein, Andre J. Van Wijnen, Jane B. Lian, Anthony N. Imbalzano, Martin A. Montecino, Sayyed K. Zaidi, Jane B. Lian, Jeffrey A. Nickerson, and Janet L. Stein (Critical reviews in eukaryotic gene expression)

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Social Support to Empower Parents (STEP): an intervention for parents of young children newly diagnosed with type 1 diabetes, Susan Sullivan-Bolyai, Carol A. Bova, Katherine Leung, Allison Trudeau, Mary M. Lee, and Philip Gruppuso (The Diabetes educator)

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Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis, Yumi Uetake and Greenfield Sluder (Current biology : CB)

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The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells, Margaretha Van der Deen, Jacqueline Akech, Tao Wang, Thomas J. Fitzgerald, Dario C. Altieri, Lucia R. Languino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Journal of cellular biochemistry)

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Mechanisms of sperm-egg interactions: between sugars and broken bonds, Pablo E. Visconti and Harvey M. Florman (Science signaling)

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Blood lead levels and delayed onset of puberty in a longitudinal study of Russian boys, Paige L. Williams, Oleg Sergeyev, Mary M. Lee, Susan A. Korrick, Jane S. Burns, Olivier Humblet, Julie T. Del Prato, Boris Revich, and Russ Hauser (Pediatrics)

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Androgen profiles during pubertal Leydig cell development in mice, Xiufeng Wu, Ramamani Arumugam, Ningning Zhang, and Mary M. Lee (Reproduction (Cambridge, England))

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PAMM: a redox regulatory protein that modulates osteoclast differentiation, Yan Xu, Leslie R. Morse, Raquel Assed Bezerra da Silva, Paul R. Odgren, Hajime Sasaki, Philip Stashenko, and Ricardo A. Battaglino (Antioxidants and redox signaling)

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Subnuclear localization and intranuclear trafficking of transcription factors, Sayyed K. Zaidi, Ricardo F. Medina, Shirwin M. Pockwinse, Rachit Bakshi, Krishna P. Kota, Syed A. Ali, Daniel W. Young, Jeffrey A. Nickerson, Amjad Javed, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein (Methods in molecular biology (Clifton, N.J.))

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Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information, Sayyed K. Zaidi, Daniel W. Young, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Molecular and cellular biology)

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Mitotic bookmarking of genes: a novel dimension to epigenetic control, Sayyed K. Zaidi, Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein (Nature reviews. Genetics)

Submissions from 2009

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Prostate cancer regulatory networks, Dario C. Altieri, Lucia R. Languino, Jane B. Lian, Janet L. Stein, Irwin Leav, Andre J. Van Wijnen, Zhong Jiang, and Gary S. Stein (Journal of cellular biochemistry)

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Book Review: Current Hypotheses and Research Milestones in Alzheimer's Disease, Athena Andreadis (Journal of Alzheimer's Disease)

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Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis, Rami I. Aqeilan, John P. Hagan, Alain de Bruin, Maysoon Rawahneh, Zaidoun Salah, Eugenio Gaudio, Hasan Siddiqui, Stefano Volinia, Hansjuerg Alder, Jane B. Lian, Gary S. Stein, and Carlo M. Croce (Endocrinology)

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PSD-95 Tyrosine Phosphorylation and Pyk2 Binding Are Regulated by Cdk5, Michael Bianchetta and Maria A. Morabito (Society for Neuroscience's 2009 Annual Meeting)

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Effects of review on medical students' recall of different types of neuroanatomical content, Susan Billings-Gagliardi and Kathleen M. Mazor (Academic medicine : journal of the Association of American Medical Colleges)

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Predictors of serum dioxins and PCBs among peripubertal Russian boys, Jane S. Burns, Paige L. Williams, Oleg Sergeyev, Susan Korrick, Mary M. Lee, Boris Revich, Larisa Altshul, Donald G. Patterson, Wayman E. Turner, Larry L. Needham, Igor Saharov, and Russ Hauser (Environmental health perspectives)

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Changing nuclear landscape and unique PML structures during early epigenetic transitions of human embryonic stem cells, John T. Butler, Lisa L. Hall, Kelly P. Smith, and Jeanne B. Lawrence (Journal of cellular biochemistry)

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Consensus statement on the use of gonadotropin-releasing hormone analogs in children, Jean-Claude Carel, Erica A. Eugster, Alan Rogol, Lucia Ghizzoni, Mark R. Palmert, Mary M. Lee, and ESPE-LWPES GnRH Analogs Consensus Conference Group (Pediatrics)

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Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination, Xin-Zi Chi, Jiyeon Kim, Yong-Hee Lee, Jung-Won Lee, Kyeong-Sook Lee, Hee-Jun Wee, Wun-Jae Kim, Woo-Yoon Park, Byung-Chul Oh, Gary S. Stein, Yoshiaki Ito, Andre J. Van Wijnen, and Suk-Chul Bae (Cancer research)

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The ING gene family in the regulation of cell growth and tumorigenesis, Andrew H. Coles and Stephen N. Jones (Journal of cellular physiology)

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Aurora-A kinase is essential for bipolar spindle formation and early development, Dale O. Cowley, Jaime A. Rivera-Pérez, Mark Schliekelman, Yizhou Joseph He, Trudy G. Oliver, Lucy Lu, Ryan O'Quinn, E. D. Salmon, Terry Magnuson, and Terry Van Dyke (Molecular and cellular biology)

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Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency, Jessica Lynn Crowley, Tara C. Smith, Zhiyou Fang, Norio Takizawa, and Elizabeth J. Luna (Molecular biology of the cell)

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SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2, Fernando Cruzat, Berta Henriquez, Alejandro Villagra, Matias Hepp, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, Anthony N. Imbalzano, Gary S. Stein, and Martin A. Montecino (Biochemistry)

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Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer, Kakoli Das, David Tai Leong, Anurag Gupta, Liang Shen, Thomas Putti, Gary S. Stein, Andre J. Van Wijnen, and Manuel Salto-Tellez (European journal of cancer (Oxford, England : 1990))

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Total internal reflection fluorescence (TIRF) microscopy of Chlamydomonas flagella, Benjamin D. Engel, Karl-Ferdinand Lechtreck, Tsuyoshi Sakai, Mitsuo Ikebe, George B. Witman, and Wallace F. Marshall (Methods in cell biology)

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Septoclast deficiency accompanies postnatal growth plate chondrodysplasia in the toothless (tl) osteopetrotic, colony-stimulating factor-1 (CSF-1)-deficient rat and is partially responsive to CSF-1 injections, Alison Gartland, April Mason-Savas, Meilheng Yang, Carole A. MacKay, Mark J. Birnbaum, and Paul R. Odgren (The American journal of pathology)

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Secreted frizzled related protein 1 is a target to improve fracture healing, Tripti Gaur, John J. Wixted, Sadiq Hussain, Shannon L. O'Connell, Elise F. Morgan, David C. Ayers, Barry S. Komm, Peter V. N. Bodine, Gary S. Stein, and Jane B. Lian (Journal of cellular physiology)

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The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types, Prachi N. Ghule, Zbigniew Dominski, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular physiology)

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The heparan sulfate proteoglycan (HSPG) glypican-3 mediates commitment of MC3T3-E1 cells toward osteogenesis, Larisa M. Haupt, Sadasivam Murali, Foong Kin Mun, Nadiya M. Teplyuk, Leong Fong Mei, Gary S. Stein, Andre J. Van Wijnen, Victor Nurcombe, and Simon M. Cool (Journal of cellular physiology)

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The influence of endocrine disruptors on pubertal timing, Elka Jacobson-Dickman and Mary M. Lee (Current opinion in endocrinology, diabetes, and obesity)

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Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice, Ya-Huei Kuo, Sayyed K. Zaidi, Svetlana Gornostaeva, Toshihisa Komori, Gary S. Stein, and Lucio H. Castilla (Blood)

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Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro, Nichole E. Lapointe, Peleg M. Horowitz, Angela L. Guillozet-Bongaarts, Andres Silva, Athena Andreadis, and Lester I. Binder (Biochemistry)

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The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella, Karl-Ferdinand Lechtreck, Eric C. Johnson, Tsuyoshi Sakai, Deborah A. Cochran, Bryan A. Ballif, John Rush, Gregory J. Pazour, Mitsuo Ikebe, and George B. Witman (The Journal of cell biology)

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HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B, Karl-Ferdinand Lechtreck, Scott Luro, Junya Awata, and George B. Witman (Cell motility and the cytoskeleton)

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High-speed digital imaging of ependymal cilia in the murine brain, Karl-Ferdinand Lechtreck, Michael J. Sanderson, and George B. Witman (Methods in cell biology)

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Tropomyosin and the steric mechanism of muscle regulation, William Lehman and Roger W. Craig (Advances in experimental medicine and biology)

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Structural basis for the activation of muscle contraction by troponin and tropomyosin, William Lehman, Agnieszka Galinska-Rakoczy, Victoria Hatch, Larry S. Tobacman, and Roger W. Craig (Journal of molecular biology)

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Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation, Zhaoyong Li, Mohammad Q. Hassan, Mohammed Jafferji, Rami I. Aqeilan, Ramiro Garzon, Carlo M. Croce, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian (The Journal of biological chemistry)

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CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P, Partha Mitra, Prachi N. Ghule, Margaretha Van der Deen, Ricardo F. Medina, Ronglin Xie, William F. Holmes, Xin Ye, Keiichi I. Nakayama, J. Wade Harper, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen (Journal of cellular physiology)

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The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells, Samisubbu R. Naidu, Ian M. Love, Anthony N. Imbalzano, Steven R. Grossman, and Elliot J. Androphy (Oncogene)

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The biochemistry of RNA metabolism studied in situ, Jeffrey A. Nickerson (RNA biology)

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Do Atypical Antipsychotic Agents Trigger Autoimmune Diabetes?, Benjamin U. Nwosu, Olga T. Hardy, Amanda Angelescu, Leslie A. Soyka, and Mary M. Lee (Endocrinologist)

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Pseudohypoparathyroidism type 1a and insulin resistance in a child, Benjamin U. Nwosu and Mary M. Lee (Nature reviews. Endocrinology)

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The Chlamydomonas Flagellum as a Model for Human Ciliary Disease, Gregory J. Pazour and George B. Witman (The Chlamydomonas Sourcebook)

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Refined genomic localization of the genetic lesion in the osteopetrosis (op) rat and exclusion of three positional and functional candidate genes, Clcn7, Atp6v0c, and Slc9a3r2, B. Perdu, Paul R. Odgren, Liesbeth van Wesenbeeck, K. Jennes, Carole A. MacKay, and W. Van Hul (Calcified tissue international)

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Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1), Barry P. Pereira, Ye-fang Zhou, Anurag Gupta, David T. Leong, Khin Zarchi Zarchi Aung, Ling Ling, Robert W. H. Pho, Mario Galindo, Manuel Salto-Tellez, Gary S. Stein, Simon M. Cool, Andre J. Van Wijnen, and Saminathan S. Nathan (Journal of cellular physiology)

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Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression, Jitesh Pratap, Karen M. Imbalzano, Jean. M. Underwood, Nathalie Cohet, Karthiga Devi Gokul, Jacqueline Akech, Andre J. Van Wijnen, Janet L. Stein, Anthony N. Imbalzano, Jeffrey A. Nickerson, Jane B. Lian, and Gary S. Stein (Cancer research)

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Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells, Inga A. San Martin, Nelson Varela, Marcia Gaete, Karina Villegas, Mariana Osorio, Julio Tapia, Marcelo Antonelli, Edna E. Mancilla, Barry P. Pereira, Saminathan S. Nathan, Jane B. Lian, Janet L. Stein, Gary S. Stein, Andre J. Van Wijnen, and Mario Galindo (Journal of cellular physiology)

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Pluripotency: toward a gold standard for human ES and iPS cells, Kelly P. Smith, Mai X. Luong, and Gary S. Stein (Journal of cellular physiology)

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Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan (Annals of the New York Academy of Sciences)

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Transcription-factor-mediated epigenetic control of cell fate and lineage commitment, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan (Biochemistry and cell biology = Biochimie et biologie cellulaire)

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Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation, Marcela Stuardo, Milka Martinez, Karla Hildago, Martin A. Montecino, Amjad Javed, Jane B. Lian, Gary S. Stein, Janet L. Stein, and Soraya E. Gutierrez (Journal of cellular physiology)

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The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts, Nadiya M. Teplyuk, Larisa M. Haupt, Ling Ling, Christian Dombrowski, Foong Kin Mun, Saminathan S. Nathan, Jane B. Lian, Janet L. Stein, Gary S. Stein, Simon M. Cool, and Andre J. Van Wijnen (Journal of cellular biochemistry)

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The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts, Nadiya M. Teplyuk, Ying Zhang, Yang Lou, John R. Hawse, Mohammad Q. Hassan, Viktor Teplyuk, Jitesh Pratap, Mario Galindo, Janet L. Stein, Gary S. Stein, Jane B. Lian, and Andre J. Van Wijnen (Molecular endocrinology (Baltimore, Md.))

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The tail binds to the head-neck domain, inhibiting ATPase activity of myosin VIIA, Nobuhisa Umeki, HyunSuk Jung, Shinya Watanabe, Tsuyoshi Sakai, Xiang-Dong Li, Reiko Ikebe, Roger W. Craig, and Mitsuo Ikebe (Proceedings of the National Academy of Sciences of the United States of America)

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Heterogeneous nuclear ribonucleoprotein E3 modestly activates splicing of tau exon 10 via its proximal downstream intron, a hotspot for frontotemporal dementia mutations, Yan Wang, Lei Gao, Sze-Wah Tse, and Athena Andreadis (Gene)