UMMS Affiliation

Department of Cell Biology

Date

2-24-2009

Document Type

Article

Subjects

Animals; Cell Lineage; Cell Nucleus; Cell Proliferation; *Epigenesis, Genetic; Humans; Mitosis; Transcription Factors

Abstract

Epigenetic control is required to maintain competency for the activation and suppression of genes during cell division. The association between regulatory proteins and target gene loci during mitosis is a parameter of the epigenetic control that sustains the transcriptional regulatory machinery that perpetuates gene-expression signatures in progeny cells. The mitotic retention of phenotypic regulatory factors with cell cycle, cell fate, and tissue-specific genes supports the coordinated control that governs the proliferation and differentiation of cell fate and lineage commitment.

Rights and Permissions

Copyright NRC Research Press. Published as: Biochem Cell Biol. 2009 Feb;87(1):1-6. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

19234518

Journal Title

Biochemistry and cell biology = Biochimie et biologie cellulaire

Included in

Cell Biology Commons

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