The Department of Cell and Developmental Biology at the University of Massachusetts Medical School is at the center of exciting new advances in understanding basic biological and biomedical processes to promote clinical and translational science. Research addresses the organization, assembly and activity of the regulatory machinery for cell growth and aging, differentiation and development, as well as genetic and epigenetic control of gene expression in human embryonic stem cells and lineage committed cells; with implications for treatment of cancers, bone diseases, reproductive disorders, genetic conditions and neurodegenerative and psychiatric disorders. This collection showcases the books, journal articles, book reviews, and other publications and presentations written by faculty and researchers of the Department of Cell and Developmental Biology.

Submissions from 2014

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Arf4 is required for Mammalian development but dispensable for ciliary assembly, John A. Follit, Jovenal T. San Agustin, Julie A. Jonassen, Tingting Huang, Jaime A. Rivera-Perez, Kimberly D. Tremblay, and Gregory J. Pazour (PLoS genetics)

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Stable C0T-1 repeat RNA is abundant and is associated with euchromatic interphase chromosomes, Lisa L. Hall, Dawn M. Carone, Alvin V. Gomez, Heather J. Kolpa, Meg Byron, Nitish Mehta, Frank O. Fackelmayer, and Jeanne B. Lawrence (Cell)

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Senescence-associated β-galactosidase activity marks the visceral endoderm of mouse embryos but is not indicative of senescence, Tingting Huang and Jaime A. Rivera-Perez (Genesis)

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A new role for Hedgehogs in juxtacrine signaling, Christopher A. Pettigrew, Eva Asp, and Charles P. Emerson Jr. (Mechanisms of development)

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Smurf2 regulates hematopoietic stem cell self-renewal and aging, Charusheila Ramkumar, Yahui Kong, Sally E. Trabucco, Rachel M. Gerstein, and Hong Zhang (Aging cell)

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Human skeletal muscle xenograft as a new preclinical model for muscle disorders, Yuanfan Zhang, Oliver D. King, Fedik Rahimov, Takako I. Jones, Christopher W. Ward, Jaclyn P. Kerr, Naili Liu, Charles P. Emerson Jr., Louis M. Kunkel, Terence A. Partridge, and Kathryn R. Wagner (Human molecular genetics)

Submissions from 2013

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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics, Desiree M. Baron, Laura J. Kaushansky, Catherine L. Ward, Reddy Ranjith Kumar Sama, Ru-ju Chian, Kristin J. Boggio, Alexandre J. C. Quaresma, Jeffrey A. Nickerson, and Daryl A. Bosco (Molecular neurodegeneration)

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A multifaceted FISH approach to study endogenous RNAs and DNAs in native nuclear and cell structures, Meg Byron, Lisa L. Hall, and Jeanne B. Lawrence (Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.])

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A long noncoding RNA mediates both activation and repression of immune response genes, Susan Carpenter, Daniel Aiello, Maninjay K. Atianand, Emiliano P. Ricci, Pallavi Gandhi, Lisa L. Hall, Meg Byron, Brian G. Monks, Meabh Henry-Bezy, Jeanne B. Lawrence, Luke A. J. O'Neill, Melissa J. Moore, Daniel R. Caffrey, and Katherine A. Fitzgerald (Science (New York, N.Y.))

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The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS, Ci-Di Chen, Jacob A. Sloane, Hu Li, Nurgul Aytan, Eustathia Lela Giannaris, Ella Zeldich, Jason D. Hinman, Alpaslan Dedeoglu, Douglas L. Rosene, Rashmi Bansal, Jennifer I. Leubke, Makoto Kuro-o, and Carmela R. Abraham (The Journal of neuroscience : the official journal of the Society for Neuroscience)

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Analysis of Myogenic and Candidate Disease Biomarkers in FSHD Muscle Cells, Jennifer C. J. Chen; Takako I. Jones; Oliver D. King; Kendal Hanger; Fedik Rahimov; Sachiko Homma; Mary Lou Beermann; Genila M. Bibat; Jeffrey B. Miller; Louise M. Kunkel; Kathryn R. Wagner; Peter L. Jones; and Charles P. Emerson, Jr. (UMass Center for Clinical and Translational Science Research Retreat)

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Exome sequencing to identify de novo mutations in sporadic ALS trios, Alessandra Chesi, Brett T. Staahl, Ana Jovicic, Julien Couthouis, Maria Fasolino, Alya R. Raphael, Tomohiro Yamazaki, Laura Elias, Meraida Polak, Crystal Kelly, Kelly L. Williams, Jennifer A. Fifita, Nicholas J. Maragakis, Garth A. Nicholson, Oliver D. King, Robin Reed, Gerald R. Crabtree, Ian P. Blair, Jonathan D. Glass, and Aaron D. Gitler (Nature neuroscience)

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Isolation of Chlamydomonas flagella, Branch Craige, Jason M. Brown, and George B. Witman (Current Protocols in Cell Biology)

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Notch3 Functions as a Tumor Suppressor by Controlling Cellular Senescence, Hang Cui, Yahui Kong, Mei Xu, and Hong Zhang (Cancer research)

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Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin, L. Damiano, K. M. Stewart, Nathalie Cohet, J. K. Mouw, J. N. Lakins, J. Debnath, D. Reisman, Jeffrey A. Nickerson, Anthony N. Imbalzano, and V. M. Weaver (Oncogene)

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Supervillin-mediated Suppression of p53 Protein Enhances Cell Survival, Zhiyou Fang and Elizabeth J. Luna (The Journal of biological chemistry)

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Anatomy: An Essential Textbook, Anne M. Gilroy (Cell and Developmental Biology Publications and Presentations)

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Pulmonary delivery of d-methionine is associated with an increase in ALCAR and glutathione in cochlear fluids, Yohann Grondin, Douglas A. Contanche, Otto Manneberg, Ramon Molina, J. Humberto Trevino-Villarreal, Rosalinda Sepulveda, Royce Clifford, Magda E. Bortoni, Scott Forsberg, Brian Labrecque, Larisa Altshul, Joseph D. Brain, Ronald L. Jackson, and Rick A. Rogers (Hearing research)

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beta3GnT2 null mice exhibit defective accessory olfactory bulb innervation, Timothy R. Henion, Pasil A. Madany, Ashley A. Faden, and Gerald A. Schwarting (Molecular and cellular neurosciences)

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The Scaffold attachment factor b1 (Safb1) regulates myogenic differentiation by facilitating the transition of myogenic gene chromatin from a repressed to an activated state, J. Manuel Hernandez-Hernandez, Chandrashekara Mallappa, Brian T. Nasipak, Steffi Oesterreich, and Anthony N. Imbalzano (Nucleic acids research)

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Pax3 synergizes with Gli2 and Zic1 in transactivating the Myf5 epaxial somite enhancer, Charis Himeda, Marietta V. Barro, and Charles P. Emerson Jr. (Developmental biology)

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Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene, Hayk Hovhannisyan, Ying Zhang, Mohammad Q. Hassan, Hai Wu, Carlotta Glackin, Jane B. Lian, Janet L. Stein, Martin A. Montecino, Gary S. Stein, and Andre J. Van Wijnen (Journal of cellular physiology)

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Genetic modification of the association between peripubertal dioxin exposure and pubertal onset in a cohort of Russian boys, Olivier Humblet, Susan A. Korrick, Paige L. Williams, Oleg Sergeyev, Claude Emond, Linda S. Birnbaum, Jane S. Burns, Larisa Altshul, Donald G. Patterson Jr., Wayman E. Turner, Mary M. Lee, Boris Revich, and Russ Hauser (Environmental health perspectives)

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Nuclear Shape Changes Are Induced by Knockdown of the SWI/SNF ATPase BRG1 and Are Independent of Cytoskeletal Connections, Karen M. Imbalzano, Nathalie Cohet, Qiong Wu, Jean M. Underwood, Anthony N. Imbalzano, and Jeffrey A. Nickerson (PloS one)

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Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases, Walker S. Jackson, Andrew W. Borkowski, Nicki E. Watson, Oliver D. King, Henryk Faas, Alan Jasanoff, and Susan Lindquist (Proceedings of the National Academy of Sciences of the United States of America)

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Translating dosage compensation to trisomy 21, Jun Jiang, Yuanchun Jing, Gregory J. Cost, Jen-Chieh Chiang, Heather J. Kolpa, Allison M. Cotton, Dawn M. Carone, Benjamin R. Carone, David A. Shivak, Dmitry Y. Guschin, Jocelynn R. Pearl, Edward J. Rebar, Meg Byron, Philip D. Gregory, Carolyn J. Brown, Fyodor D. Urnov, Lisa L. Hall, and Jeanne B. Lawrence (Nature)

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Molecular Mechanisms of FSH Muscular Dystrophy Pathogenesis, Peter L. Jones and Takako I. Jones (UMass Center for Clinical and Translational Science Research Retreat)

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The abbreviated pluripotent cell cycle, Kristina Kapinas, Rodrigo Grandy, Prachi N. Ghule, Ricardo F. Medina, Klaus A. Becker, Arthur B. Pardee, Sayyed K. Zaidi, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein (Journal of cellular physiology)

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FGF2-induced effects on transcriptome associated with regeneration competence in adult human fibroblasts, Olga Kashpur, David S. Lapointe, Sakthikumar Ambady, Elizabeth F. Ryder, and Tanja Dominko (BMC genomics)

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Interview: from Down's syndrome to basic epigenetics and back again, Jeanne B. Lawrence (Epigenomics)

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Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase, Karl-Ferdinand Lechtreck, Jason M. Brown, Julio L. Sampaio, Julie M. Craft, Andrej Shevchenko, James E. Evans, and George B. Witman (The Journal of cell biology)

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Flagellar central pair assembly in Chlamydomonas reinhardtii, Karl-Ferdinand Lechtreck, Travis J. Gould, and George B. Witman (Cilia)

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Sulfobetaine as a zwitterionic mediator for 3D hydroxyapatite mineralization, Pingsheng Liu and Jie Song (Biomaterials)

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Stress granules as crucibles of ALS pathogenesis, Yun R. Li, Oliver D. King, James Shorter, and Aaron D. Gitler (The Journal of cell biology)

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Modulation of Nuclear Shape by Substrate Rigidity, David B. Lovett, Nandini Shekhar, Jeffrey A. Nickerson, Kyle J. Roux, and Tanmay P. Lele (Cellular and Molecular Bioengineering)

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Avalanche-like behavior in ciliary import, William B. Ludington, Kimberly A. Wemmer, Karl-Ferdinand Lechtreck, George B. Witman, and Wallace F. Marshall (Proceedings of the National Academy of Sciences of the United States of America)

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Exome sequencing identifies a novel SMCHD1 mutation in facioscapulohumeral muscular dystrophy 2, Satomi Mitsuhashi, Steven E. Boyden, Elicia A. Estrella, Takako I. Jones, Fedik Rahimov, Timothy W. Yu, Basil T. Darras, Anthony A. Amato, Rebecca D. Folkerth, Peter L. Jones, Louis M. Kunkel, and Peter B. Kang (Neuromuscular disorders : NMD)

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Adipose Tissue Architecture and Gestational Weight Gain in Normoglycemic Pregnancies, Tiffany A. Moore Simas, Olga Gaelekman, Ningning Zhang, Milagros C. Rosal, Mary M. Lee, and Silvia Corvera (UMass Center for Clinical and Translational Science Research Retreat)

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Vitamin D status is associated with early markers of cardiovascular disease in prepubertal children, Benjamin U. Nwosu, Louise Maranda, Karen Cullen, Carol A. Ciccarelli, and Mary M. Lee (Journal of pediatric endocrinology and metabolism : JPEM)

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A new approach for the study of lung smooth muscle phenotypes and its application in a murine model of allergic airway inflammation, Jesus Paez-Cortez, Ramaswamy Krishnan, Anneliese Arno, Linh Aven, Sumati Ram-Mohan, Kruti R. Patel, Jining Lu, Oliver D. King, Xingbin Ai, and Alan Fine (PloS one)

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Regulation of mRNA Export by the PI3 kinase / AKT Signal Transduction Pathway, Alexandre Jose Christino Quaresma, Rachel Sievert, and Jeffrey A. Nickerson (Molecular biology of the cell)

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Smurf2 suppresses B-cell proliferation and lymphomagenesis by mediating ubiquitination and degradation of YY1, Charusheila Ramkumar, Hang Cui, Yahui Kong, Stephen N. Jones, Rachel M. Gerstein, and Hong Zhang (Nature communications)

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Serial Transplantation of Bone Marrow to Test Self-renewal Capacity of Hematopoietic Stem Cells In Vivo, Charusheila Ramkumar, Rachel M. Gerstein, and Hong Zhang (Methods in molecular biology (Clifton, N.J.))

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Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo, Teresa Repasy, Jinhee Lee, Simeone Marino, Nuria Martinez, Denise E. Kirschner, Gregory M. Hendricks, Stephen P. Baker MScPH, Andrew A. Wilson, Darrell N. Kotton, and Hardy Kornfeld (PLoS Pathogens)

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Cancer-testis gene expression is associated with the methylenetetrahydrofolate reductase 677 C>T polymorphism in non-small cell lung carcinoma, Kerem M. Senses, Mithat Gonen, Ahmet Rasim Barutcu, Zeynep Kalaylioglu, Murat Isbilen, Ozlen Konu, Yao T. Chen, Nasser K. Altorki, and Ali O. Gure (BMC medical genetics)

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Supervillin Binding to Myosin II and Synergism with Anillin Are Required for Cytokinesis, Tara C. Smith, Peter C. Fridy, Yinyin Li, Shruti Basil, Sneha Arjun, Ryan M. Friesen, John D. Leszyk, Brian T. Chait, Michael P. Rout, and Elizabeth J. Luna (Molecular biology of the cell)

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Telomere position effect regulates DUX4 in human facioscapulohumeral muscular dystrophy, Guido Stadler, Fedik Rahimov, Oliver D. King, Jennifer C. J. Chen, Jerome D. Robin, Kathryn R. Wagner, Jerry W. Shay, Charles P. Emerson Jr., and Woodring E. Wright (Nature structural and molecular biology)

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Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence, Eric C. Swanson, Benjamin J. Manning, Hong Zhang, and Jeanne B. Lawrence (The Journal of cell biology)

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Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice, Giovane G. Tortelote, Jose Manuel Hernandez, Alexandre J. C. Quaresma, Jeffrey A. Nickerson, Anthony N. Imbalzano, and Jaime A. Rivera-Perez (Developmental biology)

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Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms, P. Tripathi, Y. Wang, M. Coussens, K. R. Manda, A. M. Casey, C. Lin, E. Poyo, J. D. Pfeifer, N. Basappa, C. M. Bates, L. Ma, Hong Zhang, M. Pan, L. Ding, and F. Chen (Oncogene)

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Dimethyl sulfoxide (DMSO) exacerbates cisplatin-induced sensory hair cell death in zebrafish (Danio rerio), Phillip M. Uribe, Melissa A. Mueller, Julia S. Gleichman, Matthew D. Kramer, Qi Wang, Martha Sibrian-Vazquez, Robert M. Strongin, Peter S. Steyger, Douglas A. Contanche, and Jonathan I. Matsui (PloS one)

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Dux4 Target Gene Expression in Mouse Muscle Transplanted with Muscle Cells from FSHD Patients, James A. Windelborn and Charles P. Emerson, Jr. (UMass Center for Clinical and Translational Science Research Retreat)

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Structural basis of the relaxed state of a Ca2+-regulated myosin filament and its evolutionary implications, John L. Woodhead, Fa-Qing Zhao, and Roger W. Craig (Proceedings of the National Academy of Sciences of the United States of America)

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Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research, Soonsang Yoon, Guido Stadler, Mary Lou Beermann, Eric V. Schmidt, James A. Windelborn, Peter Schneiderat, Woodring E. Wright, and Jeffrey Boone Miller (Skeletal muscle)

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Stem cell labeling using polyethylenimine conjugated (alpha-NaYbF4:Tm3+)/CaF2 upconversion nanoparticles, Liang Zhao, Artem Kutikov, Jie Shen, Chunying Duan, Jie Song, and Gang Han (Theranostics)

Submissions from 2012

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A Runx2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation, Syed A. Ali, Jason Dobson, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, Sayyed K. Zaidi, and Gary S. Stein (Journal of cell science)

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TRAP-1, the mitochondrial Hsp90, Dario C. Altieri, Gary S. Stein, Jane B. Lian, and Lucia R. Languino (Biochimica et biophysica acta)

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Tau Splicing and the Intricacies of Dementia, Athena Andreadis (Journal of cellular physiology)

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Supervillin couples myosin-dependent contractility to podosomes and enables their turnover, Ridhirama Bhuwania, Susanne Cornfine, Zhiyou Fang, Marcus Kruger, Elizabeth J. Luna, and Stefan Linder (Journal of cell science)

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Bone marrow-derived heparan sulfate potentiates the osteogenic activity of bone morphogenetic protein-2 (BMP-2), Diah S. Bramono, Sadasivam Murali, Bina Rai, Ling Ling, Wei Theng Poh, Zophia Xuehui Lim, Gary S. Stein, Victor Nurcombe, Andre J. Van Wijnen, and Simon M. Cool (Bone)

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A FAP46 mutant provides new insights into the function and assembly of the C1d complex of the ciliary central apparatus, Jason Brown, Christen G. Dipetrillo, Elizabeth F. Smith, and George B. Witman (Journal of cell science)

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Serum Concentrations of Organochlorine Pesticides and Growth among Russian Boys, Jane S. Burns, Paige L. Williams, Oleg Sergeyev, Susan A. Korrick, Mary M. Lee, Boris Revich, Larisa Altshul, Julie T. Del Prato, Olivier Humblet, Donald G. Patterson, Wayman E. Turner, Mikhail Starovoytov, and Russ Hauser (Environmental health perspectives)

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Heterochromatin instability in cancer: From the Barr body to satellites and the nuclear periphery, Dawn M. Carone and Jeanne B. Lawrence (Seminars in cancer biology)

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(alpha-NaYbF4:Tm(3+))/CaF2 core/shell nanoparticles with efficient near-infrared to near-infrared upconversion for high-contrast deep tissue bioimaging, Guanying Chen, Jie Shen, Tymish Y. Ohulchansky, Nayan J. Patel, Artem Kutikov, Zhipeng Li, Jie Song, Ravindra K. Pandey, Hans Agren, Paras N. Prasad, and Gang Han (ACS nano)

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Isolation, electron microscopy and 3D reconstruction of invertebrate muscle myofilaments, Roger W. Craig (Methods (San Diego, Calif.))

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The TAL effector PthA4 interacts with nuclear factors involved in RNA-dependent processes including a HMG protein that selectively binds poly(U) RNA, Tiago Anthony de Souza, Adriana Santos Soprano, Nayara Patricia Vieira de Lira, Alexandre J.C. Quaresma, Adriana Franco Paes Leme, and Celso Eduardo Benedetti (PLoS ONE)

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Neural Crest Deletion of Dlx3 Leads to Major Dentin Defects through Down-regulation of Dspp, Olivier Duverger, Angela Zah, Juliane Isaac, Hong-Wei Sun, Anne K. Bartels, Jane B. Lian, Ariane Berdal, Joonsung Hwang, and Maria I. Morasso (The Journal of biological chemistry)

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Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation under Shear Stress, Leonard C. Edelstein, Elizabeth J. Luna, Ian B. Gibson, Molly Bray, Ying Jin, Altaf Kondkar, Srikanth Nagalla, Nacima Hadjout-Rabi, Tara C. Smith, Daniel Covarrubias, Stephen N. Jones, Firdos Ahmad, Moritz Stolla, Xianguo Kong, Zhiyou Fang, Wolfgang Bergmeier, Chad Shaw, Suzanne M. Leal, and Paul F. Bray (Circulation)

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The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function, Benjamin D. Engel, Hiroaki Ishikawa, Kimberly A. Wemmer, Stefan Geimer, Ken-ichi Wakabayashi, Masafumi Hirono, Branch Craige, Gregory J. Pazour, George B. Witman, Ritsu Kamiya, and Wallace F. Marshall (The Journal of cell biology)

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Farm residence and reproductive health among boys in rural South Africa, Rene Glynnis English, Melissa Perry, Mary M. Lee, Elaine Hoffman, Steven Delport, and Mohamed Agiel Dalvie (Environment international)

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The Varus Knee Reveals Differential Expression Patterns of miRNAs in Spared vs. Non-spared Compartments, Paul J. Fanning, Brian Ayers, Marie Walcott, Gary S. Stein, David C. Ayers, and Jane B. Lian (UMass Center for Clinical and Translational Science Research Retreat)

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Etiology of Experimental Osteoarthritis: Early Events and Potential Clinical Implications, Paul J. Fanning, Jason Silva, Julianne Marvin, Kirti Basil, Marie Walcott, and David C. Ayers (UMass Center for Clinical and Translational Science Research Retreat)

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An N-terminal, 830 residues intrinsically disordered region of the cytoskeleton-regulatory protein supervillin contains Myosin II- and F-actin-binding sites, Stanislav O. Fedechkin, Jacob Brockerman, Elizabeth J. Luna, Michail Yu. Lobanov, Oxana V. Galzitskaya, and Serge L. Smirnov (Journal of biomolecular structure and dynamics)

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Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis, Hugh S. Gannon and Stephen N. Jones (Genes and cancer)

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ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice, Hugh S. Gannon, Bruce A. Woda, and Stephen N. Jones (Cancer cell)

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A stereological study of the numbers of neurons and glia in the primary visual cortex across the lifespan of male and female rhesus monkeys, Eustathia Lela Giannaris and Douglas L. Rosene (The Journal of comparative neurology)

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Atlas of Anatomy, Anne M. Gilroy, Brian R. MacPherson, and Lawrence M. Ross (Cell and Developmental Biology Publications and Presentations)

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Vitamin k-dependent carboxylation of osteocalcin: friend or foe, Caren M. Gundberg, Jane B. Lian, and Sarah L. Booth (Advances in nutrition (Bethesda, Md.))

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Chd2 interacts with H3.3 to determine myogenic cell fate, Akihito Harada, Seiji Okada, Daijiro Konno, Jun Odawara, Tomohiko Yoshimi, Saori Yoshimura, Hiromi Kumamaru, Hirokazu Saiwai, Toshiaki Tsubota, Hitoshi Kurumizaka, Koichi Akashi, Taro Tachibana, Anthony N. Imbalzano, and Yasuyuki Ohkawa (The EMBO journal)

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The interrelationship between APC/C and Plk1 activities in centriole disengagement, Toshiyuki Hatano and Greenfield Sluder (Biology open)

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Heparan Sulfate Enhances the Self-Renewal and Therapeutic Potential of Mesenchymal Stem Cells from Human Adult Bone Marrow, Torben Helledie, Christian Dombrowski, Bina Rai, Zophia X.H. Lim, Ian Lee Hock Hin, David A. Rider, Gary S. Stein, Wanjin Hong, Andre J. Van Wijnen, James H. Hui, Victor Nurcombe, and Simon M. Cool (Stem cells and development)

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Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells, Hee-Jeong Im, Xin Li, Jae-Sung Kim, Michael B. Ellman, Gary S. Stein, Brian Cole, Ranjan KC, Gabriella Cs-Szabo, and Andre J. Van Wijnen (Journal of cellular physiology)

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Paternal RLIM/Rnf12 Is a Survival Factor for Milk-Producing Alveolar Cells, Baowei Jiao, Hong Ma, Maxim N. Shokhirev, Alexander Drung, Qin Yang, JongDae Shin, Shaolei Lu, Meg Byron, Sundeep Kalantry, Arthur M. Mercurio, Jeanne B. Lawrence, Alexander Hoffmann, and Ingolf Bach (Cell)

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miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma, Kevin B. Jones, Zaidoun Salah, Sara Del Mare, Marco Galasso, Eugenio Gaudio, Gerard J. Nuovo, Francesca Lovat, Kimberly T. LeBlanc, Jeff Patatini, R. Lor Randall, Stefano Volinia, Gary S. Stein, Carlo M. Croce, Jane B. Lian, and Rami I. Aqeilan (Cancer research)

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Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport, Nicholas M. Kanaan, Gerardo Morfini, Gustavo Pigino, Nichole E. Lapointe, Athena Andreadis, Yuyu Song, Ellen Leitman, Lester I. Binder, and Scott T. Brady (Neurobiology of aging)

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Protein Arginine Methyltransferase 7 Regulates Cellular Response to DNA Damage by Methylating Promoter Histones H2A and H4 of the Polymerase delta Catalytic Subunit Gene, POLD1, Vrajesh Karkhanis, Li Wang, Sookil Tae, Yu-Jie Hu, Anthony N. Imbalzano, and Said Sif (The Journal of biological chemistry)

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Lactoferricin mediates anabolic and anti-catabolic effects in the intervertebral disc, Jae-Sung Kim, Michael B. Ellman, Howard S. An, Dongyao Yan, Andre J. Van Wijnen, Gillian Murphy, David W. Hoskin, and Hee-Jeong Im (Journal of cellular physiology)

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Olfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance, Thomas K. Knott, Pasil A. Madany, Ashley A. Faden, Mei Xu, Jorg Strotmann, Timothy R. Henion, and Gerald A. Schwarting (Neural development)

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Protein Arginine Methyltransferase 5 (Prmt5) Promotes Gene Expression of Peroxisome Proliferator-Activated Receptor gamma2 (PPARgamma2) and Its Target Genes during Adipogenesis, Scott E. LeBlanc, Silvana Konda, Qiong Wu, Yu-Jie Hu, Christine M. Oslowski, Said Sif, and Anthony N. Imbalzano (Molecular endocrinology (Baltimore, Md.))

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MicroRNA control of bone formation and homeostasis, Jane B. Lian, Gary S. Stein, Andre J. Van Wijnen, Janet L. Stein, Mohammad Q. Hassan, Tripti Gaur, and Ying Zhang (Nature reviews. Endocrinology)

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Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family, Xin Li, Michael B. Ellman, Jeffrey S. Kroin, Di Chen, Dongyao Yan, Katalin Mikecz, K. C. Ranjan, Xiao Guozhi, Gary S. Stein, Su-Gwan Kim, Brian Cole, Andre J. Van Wijnen, and Hee-Jeong Im (Journal of cellular biochemistry)

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pHEMA-nHA Encapsulation and Delivery of Vancomycin and rhBMP-2 Enhances its Role as a Bone Graft Substitute, Xinning Li, Jianwen Xu, Tera M. Filion Potts, David C. Ayers, and Jie Song (Clinical orthopaedics and related research)

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Identification of RUNX3 as a component of the MST/Hpo signaling pathway, Boram Min, Min-Kyu Kim, Joo-Won Zhang, Jiyeon Kim, Kwang-Chul Chung, Byung-Chul Oh, Gary S. Stein, Yong-Hee Lee, Andre J. Van Wijnen, and Suk-Chul Bae (Journal of cellular physiology)

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Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress, Raymond S. Oh, Wen-Chi Pan, Abdullah Yalcin, Hong Zhang, Tomas R. Guilarte, Gokhan S. Hotamisligil, David C. Christiani, and Quan Lu (The Journal of biological chemistry)

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Smurf2 regulates the senescence response and suppresses tumorigenesis in mice, Charusheila Ramkumar, Yahui Kong, Hang Cui, Suyang Hao, Stephen N. Jones, Rachel M. Gerstein, and Hong Zhang (Cancer research)

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The architectural organization of human stem cell cycle regulatory machinery, Gary S. Stein, Janet L. Stein, Andre J. Van Wijnen, Jane B. Lian, Martin A. Montecino, Ricardo F. Medina, Kristina Kapinas, Prachi N. Ghule, Rodrigo Grandy, Sayyed K. Zaidi, and Klaus A. Becker (Current pharmaceutical design)

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C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1, Chiranthani Sumanasekera, Olga Kelemen, Monique Beullens, Brandon E. Aubol, Joseph A. Adams, Manjula Sunkara, Andrew Morris, Mathieu Bollen, Athena Andreadis, and Stefan Stamm (Nucleic acids research)

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A fast and sensitive alternative for beta-galactosidase detection in mouse embryos, Sakthi Sundararajan, Maki Wakamiya, Richard R. Behringer, and Jaime A. Rivera-Perez (Development (Cambridge, England))

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Evolution of the Voltage Sensor Domain of the Voltage-Sensitive Phosphoinositide Phosphatase, VSP/TPTE, Suggests a Role as a Proton Channel in Eutherian Mammals, Keith A. Sutton, Melissa K. Jungnickel, Luca Jovine, and Harvey M. Florman (Molecular biology and evolution)

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Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility, Margaretha Van der Deen, Jacqueline Akech, David S. Lapointe, Sneha Gupta, Daniel W. Young, Martin A. Montecino, Mario Galindo, Jane B. Lian, Janet L. Stein, Gary S. Stein, and Andre J. Van Wijnen (The Journal of biological chemistry)