Submissions from 2009
Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice, Ya-Huei Kuo, Sayyed K. Zaidi, Svetlana Gornostaeva, Toshihisa Komori, Gary S. Stein, and Lucio H. Castilla
Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan
Transcription-factor-mediated epigenetic control of cell fate and lineage commitment, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network, Sayyed K. Zaidi, Christopher R. Dowdy, Andre J. Van Wijnen, Jane B. Lian, Azra Raza, Janet L. Stein, Carlo M. Croce, and Gary S. Stein
Submissions from 2008
Phenotypic transcription factors epigenetically mediate cell growth control, Syed A. Ali, Sayyed K. Zaidi, Caroline S. Dacwag, Nunciada Salma, Daniel W. Young, A. Rauf Shakoori, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Anthony N. Imbalzano, Gary S. Stein, and Janet L. Stein
The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes, Rachit Bakshi, Sayyed K. Zaidi, Sandhya Pande, Mohammad Q. Hassan, Daniel W. Young, Martin A. Montecino, Jane B. Lian, Andre J. Van Wijnen, Janet L. Stein, and Gary S. Stein
Mutations in Hydin impair ciliary motility in mice, Karl-Ferdinand Lechtreck, Philippe Delmotte, Michael L. Robinson, Michael J. Sanderson, and George B. Witman
The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif, Ricardo F. Medina, Timothy F. Buck, Sayyed K. Zaidi, Angela Miele, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival, Ricardo F. Medina, Sayyed K. Zaidi, Chang-Gong Liu, Janet L. Stein, Andre J. Van Wijnen, Carlo M. Croce, and Gary S. Stein
Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes, Sandhya Pande, Syed A. Ali, Christopher R. Dowdy, Sayyed K. Zaidi, Kosei Ito, Yoshiaki Ito, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. Van Wijnen, and Gary S. Stein
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells, Jitesh Pratap, John J. Wixted, Tripti Gaur, Sayyed K. Zaidi, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, and Jane B. Lian
Nuclear microenvironments and cancer, Gary S. Stein, James R. Davie, J. Randy Knowlton, and Sayyed K. Zaidi
Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer, Gary S. Stein, Sayyed K. Zaidi, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, Martin A. Montecino, Daniel W. Young, Amjad Javed, Jitesh Pratap, Je-Yong Choi, Syed A. Ali, Sandhya Pande, and Mohammad Q. Hassan
Submissions from 2007
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella, Kaiyao Huang, Dennis R. Diener, Aaron Mitchell, Gregory J. Pazour, George B. Witman, and Joel L. Rosenbaum
The Chlamydomonas genome reveals the evolution of key animal and plant functions, Sabeeha S. Merchant, Simon E. Prochnik, George B. Witman, Gregory J. Pazour, Daniel S. Rokhsar, and Arthur R. Grossman
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential, Sayyed K. Zaidi, Sandhya Pande, Jitesh Pratap, Tripti Gaur, Simina R. Grigoriu, Syed A. Ali, Janet L. Stein, Jane B. Lian, Andre J. Van Wijnen, and Gary S. Stein
Submissions from 2006
Radial spoke proteins of Chlamydomonas flagella, Pinfen Yang, Dennis R. Diener, Chun Yang, Takahiro Kohno, Gregory J. Pazour, Jennifer M. Dienes, Nathan S. Agrin, Stephen M. King, Winfield S. Sale, Ritsu Kamiya, Joel L. Rosenbaum, and George B. Witman
Submissions from 2005
Differential light chain assembly influences outer arm dynein motor function, Linda M. DiBella, Oksana Gorbatyuk, Miho Sakato, Ken-ichi Wakabayashi, Ramila S. Patel-King, Gregory J. Pazour, George B. Witman, and Stephen M. King
Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes, Gregory J. Pazour, Nathan S. Agrin, Bethany L. Walker, and George B. Witman
Cytoplasmic dynein nomenclature, K. Kevin Pfister, Elizabeth M. C. Fisher, Ian R. Gibbons, Thomas S. Hays, Erika L. F. Holzbaur, J. Richard McIntosh, Mary E. Porter, Trina A. Schroer, Kevin T. Vaughan, George B. Witman, Stephen M. King, and Richard B. Vallee
Submissions from 2004
Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay, Amjad Javed, Sayyed K. Zaidi, Soraya E. Gutierrez, Christopher J. Lengner, Kimberly Stacy Harrington, Hayk Hovhannisyan, Brian C. Cho, Jitesh Pratap, Shirwin M. Pockwinse, Martin A. Montecino, Andre J. Van Wijnen, Jane B. Lian, Janet L. Stein, and Gary S. Stein
The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the basal body area, Shixuan Wang, Ying Luo, Patricia D. Wilson, George B. Witman, and Jing Zhou
Submissions from 2003
The vertebrate primary cilium is a sensory organelle, Gregory J. Pazour and George B. Witman
Cell motility: deaf Drosophila keep the beat, George B. Witman
Submissions from 2002
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease, Gregory J. Pazour, Jovenal T. San Agustin, John A. Follit, Joel L. Rosenbaum, and George B. Witman
Intraflagellar transport, Joel L. Rosenbaum and George B. Witman
Submissions from 2001
Forward and reverse genetic analysis of microtubule motors in Chlamydomonas, Gregory J. Pazour and George B. Witman
Transport and arrangement of the outer-dynein-arm docking complex in the flagella of Chlamydomonas mutants that lack outer dynein arms, Ken-ichi Wakabayashi, Saeko Takada, George B. Witman, and Ritsu Kamiya
Submissions from 1999
An insertional mutant of Chlamydomonas reinhardtii with defective microtubule positioning, Cynthia J. Horst, Douglas J. Fishkind, Gregory J. Pazour, and George B. Witman
Rotation of the central pair microtubules in eukaryotic flagella, Charlotte K. Omoto, Ian R. Gibbons, Ritsu Kamiya, Chikako Shingyoji, Keiichi Takahashi, and George B. Witman
Submissions from 1998
A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT), Gregory J. Pazour, Curtis G. Wilkerson, and George B. Witman
The catalytic subunit of the cAMP-dependent protein kinase of ovine sperm flagella has a unique amino-terminal sequence, Jovenal T. San Agustin, John D. Leszyk, Lydia M. Nuwaysir, and George B. Witman
Submissions from 1997
The Chlamydomonas reinhardtii ODA3 gene encodes a protein of the outer dynein arm docking complex, Anthony Koutoulis, Gregory J. Pazour, Curtis G. Wilkerson, Kazuo Inaba, Hong Sheng, Saeko Takada, and George B. Witman
Functional interaction between Chlamydomonas outer arm dynein subunits: the gamma subunit suppresses the ATPase activity of the alpha beta dimer, Ken-ichi Nakamura, Curtis G. Wilkerson, and George B. Witman
Submissions from 1995
Reactivation of Chlamydomonas cell models, Cynthia J. Horst and George B. Witman
The 78,000-M(r) intermediate chain of Chlamydomonas outer arm dynein is a microtubule-binding protein, Stephen M. King, Ramila S. Patel-King, Curtis G. Wilkerson, and George B. Witman
Assay of Chlamydomonas phototaxis, Anthony G. Moss, Gregory J. Pazour, and George B. Witman
Interspecies conservation of outer arm dynein intermediate chain sequences defines two intermediate chain subclasses, Kazuo Ogawa, Ritsu Kamiya, Curtis G. Wilkerson, and George B. Witman
Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii, Gregory J. Pazour, Oleg A. Sineshchekov, and George B. Witman
Detection of flagellar protein kinases on polyvinylidene difluoride membranes following sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Jovenal T. San Agustin and George B. Witman
Isolation of ram sperm flagella, Jovenal T. San Agustin and George B. Witman
Preparation and reactivation of demembranated, cytosol-free ram spermatozoa, Jovenal T. San Agustin and George B. Witman
The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly, Curtis G. Wilkerson, Stephen M. King, Anthony Koutoulis, Gregory J. Pazour, and George B. Witman
Submissions from 1994
Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein, Stephen M. King and George B. Witman
Novel touch-induced, Ca(2+)-dependent phobic response in a flagellate green alga, Georg Kreimer and George B. Witman
Role of cAMP in the reactivation of demembranated ram spermatozoa, Jovenal T. San Agustin and George B. Witman
Molecular analysis of the gamma heavy chain of Chlamydomonas flagellar outer-arm dynein, Curtis G. Wilkerson, Stephen M. King, and George B. Witman
Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes, Paul Zamecnik, John Aghajanian, Mary Zamecnik, John Goodchild, and George B. Witman
Submissions from 1993
ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance, Cynthia J. Horst and George B. Witman
A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain, Hitoshi Sakakibara, Saeko Takada, Stephen M. King, George B. Witman, and Ritsu Kamiya
Reactivation of demembranated, cytosol-free ram spermatozoa, Jovenal T. San Agustin and George B. Witman
Chlamydomonas phototaxis, George B. Witman
Submissions from 1992
The motile beta/IC1 subunit of sea urchin sperm outer arm dynein does not form a rigor bond, Anthony G. Moss, Jean-Luc Gatti, and George B. Witman
The alpha subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules, Anthony G. Moss, Winfield S. Sale, Laura A. Fox, and George B. Witman
Axonemal dyneins, George B. Witman
Submissions from 1991
Demembranation and reactivation of mammalian spermatozoa from golden hamster and ram, Sumio Ishijima and George B. Witman
The Mr 78,000 intermediate chain of Chlamydomonas outer arm dynein interacts with alpha-tubulin in situ, Stephen M. King, Curtis G. Wilkerson, and George B. Witman
Purification and characterization of Salmo gairdneri outer arm dynein, Anthony G. Moss, Jean-Luc Gatti, Stephen M. King, and George B. Witman
Submissions from 1990
Outer-arm dynein from trout spermatozoa: substructural organization, Stephen M. King, Jean-Luc Gatti, Anthony G. Moss, and George B. Witman
Localization of an intermediate chain of outer arm dynein by immunoelectron microscopy, Stephen M. King and George B. Witman
Submissions from 1989
Outer arm dynein from trout spermatozoa. Purification, polypeptide composition, and enzymatic properties, Jean-Luc Gatti, Stephen M. King, Anthony G. Moss, and George B. Witman
Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Nucleotide binding sites, Stephen M. King, Boyd E. Haley, and George B. Witman
Submissions from 1988
Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Location of epitopes and protease-sensitive sites, Stephen M. King and George B. Witman
Structure of the gamma heavy chain of the outer arm dynein from Chlamydomonas flagella, Stephen M. King and George B. Witman
Submissions from 1987
Flagellar movement of intact and demembranated, reactivated ram spermatozoa, Sumio Ishijima and George B. Witman
Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Masses of chains and sites of ultraviolet-induced vanadate-dependent cleavage, Stephen M. King and George B. Witman
A two-step procedure for efficient electrotransfer of both high-molecular-weight (greater than 400,000) and low-molecular-weight (less than 20,000) proteins, Tim Otter, Stephen M. King, and George B. Witman
Submissions from 1986
Purification and characterization of Chlamydomonas flagellar dyneins, Stephen M. King, Tim Otter, and George B. Witman
Isolation of Chlamydomonas flagella and flagellar axonemes, George B. Witman
Submissions from 1985
Basal bodies and associated structures are not required for normal flagellar motion or phototaxis in the green alga Chlorogonium elongatum, Harold J. Hoops and George B. Witman
Characterization of monoclonal antibodies against Chlamydomonas flagellar dyneins by high-resolution protein blotting, Stephen M. King, Tim Otter, and George B. Witman
Labeling of Chlamydomonas 18 S dynein polypeptides by 8-azidoadenosine 5'-triphosphate, a photoaffinity analog of ATP, K. Kevin Pfister, Boyd E. Haley, and George B. Witman
Submissions from 1984
Flagellar waveform and rotational orientation in a Chlamydomonas mutant lacking normal striated fibers, Harold J. Hoops, Robin L. Wright, Jonathan W. Jarvik, and George B. Witman
Submicromolar levels of calcium control the balance of beating between the two flagella in demembranated models of Chlamydomonas, Ritsu Kamiya and George B. Witman
The photoaffinity probe 8-azidoadenosine 5'-triphosphate selectively labels the heavy chain of Chlamydomonas 12 S dynein, K. Kevin Pfister, Boyd E. Haley, and George B. Witman
Subfractionation of Chlamydomonas 18 S dynein into two unique subunits containing ATPase activity, K. Kevin Pfister and George B. Witman
Submissions from 1983
Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella, Harold J. Hoops and George B. Witman
Submissions from 1982
Purification and polypeptide composition of dynein ATPases from Chlamydomonas flagella, K. Kevin Pfister, Rose B. Fay, and George B. Witman
Synthesis, transport, and utilization of specific flagellar proteins during flagellar regeneration in Chlamydomonas, Stephen P. Remillard and George B. Witman
Dynein arm conformation and mechanochemical transduction in the eukaryotic flagellum, George B. Witman and N. Minervini
Role of calmodulin in the flagellar axoneme: effect of phenothiazines on reactivated axonemes of Chlamydomonas, George B. Witman and N. Minervini
Submissions from 1981
Functionally significant central-pair rotation in a primitive eukaryotic flagellum, Charlotte K. Omoto and George B. Witman
Submissions from 1980
Calcium control of waveform in isolated flagellar axonemes of Chlamydomonas, Matthew Bessen, Rose B. Fay, and George B. Witman
Purification of calmodulin from Chlamydomonas: calmodulin occurs in cell bodies and flagella, Stephen E. Gitelman and George B. Witman
Submissions from 1978
Effects of adenylyl imidodiphosphate, a nonhydrolyzable adenosine triphosphate analog, on reactivated and rigor wave sea urchin sperm, Stephen M. Penningroth and George B. Witman
Chlamydomonas flagellar mutants lacking radial spokes and central tubules. Structure, composition, and function of specific axonemal components, George B. Witman, J. Plummer, and Greta Sander
Submissions from 1976
Tubulin requires tau for growth onto microtubule initiating sites, George B. Witman, Don W. Cleveland, Murray D. Weingarten, and Marc W. Kirschner
Submissions from 1975
The site of in vivo assembly of flagellar microtubules, George B. Witman
Submissions from 1974
Directionality of brain microtubule assembly in vitro, William L. Dentler, Sandra Granett, George B. Witman, and Joel L. Rosenbaum
Submissions from 1972
Chlamydomonas flagella. I. Isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes, George B. Witman, K. Carlson, J. Berliner, and Joel L. Rosenbaum
Chlamydomonas flagella. II. The distribution of tubulins 1 and 2 in the outer doublet microtubules, George B. Witman, K. Carlson, and Joel L. Rosenbaum
Submissions from 1971
Comparison of the microtubule proteins of neuroblastoma cells, brain, and Chlamydomonas flagella, Joanna B. Olmsted, George B. Witman, K. Carlson, and Joel L. Rosenbaum