Publications from 2004
Molecular biology of gastric cancer: Helicobacter infection and gastric adenocarcinoma: bacterial and host factors responsible for altered growth signaling, Calin Stoicov, Reza Saffari, Xun Cai, Chhaya Hasyagar, and JeanMarie Houghton
Coinfection modulates inflammatory responses and clinical outcome of Helicobacter felis and Toxoplasma gondii infections, Calin Stoicov, Mark T. Whary, Arlin B. Rogers, Frederick S. Lee, Kristine Klucevsek, Hanchen Li, Xun Cai, Reza Saffari, Zhongming Ge, Imtiaz A. Khan, Crescent L. Combe, Andrew D. Luster, James G. Fox, and JeanMarie Houghton
Publications from 2003
Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells, Robin E. Bachelder, Elizabeth A. Lipscomb, Xuena Lin, Melissa A. Wendt, Neil H. Chadborn, Britta J. Eickholt, and Arthur M. Mercurio
Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids, Richard C. Bates, Jeffrey D. Goldsmith, Robin E. Bachelder, Courtney Brown, Masabumi Shibuya, Peter Oettgen, and Arthur M. Mercurio
Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids, Richard C. Bates and Arthur M. Mercurio
ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function, Nobuko Kawaguchi, Christina Sundberg, Marie Kveiborg, Behzad Moghadaszadeh, Meena Asmar, Nikolaj Dietrich, Charles Kumar Thodeti, Finn C. Nielsen, Peter Moller, Arthur M. Mercurio, Reidar Albrechtsen, and Ulla M. Wewer
Helicobacter and gastric cancer disease mechanisms: host response and disease susceptibility, Hanchen Li, Calin Stoicov, Xun Cai, Timothy C. Wang, and JeanMarie Houghton
Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells, Elizabeth A. Lipscomb, Aisling S. Dugan, Isaac Rabinovitz, and Arthur M. Mercurio
Invasive skin carcinoma--Ras and alpha6beta4 integrin lead the way, Arthur M. Mercurio
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA, Charles Kumar Thodeti, Reidar Albrechtsen, Morten Grauslund, Meena Asmar, Christer Larsson, Yoshikazu Takada, Arthur M. Mercurio, John R. Couchman, and Ulla M. Wewer
Publications from 2002
Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4, Robin E. Bachelder, Melissa A. Wendt, and Arthur M. Mercurio
Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells, Jun Chung, Robin E. Bachelder, Elizabeth A. Lipscomb, Leslie M. Shaw, and Arthur M. Mercurio
Lessons from the alpha2 integrin knockout mouse, Arthur M. Mercurio
Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells, Annarita Morena, Sabrina Riccioni, Alessandra Marchetti, Alessandro Tartaglia Polcini, Arthur M. Mercurio, Giovanni Blandino, Ada Sacchi, and Rita Falcioni
Publications from 2001
Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells, Robin E. Bachelder, Aimee Crago, Jun Chung, Melissa A. Wendt, Leslie M. Shaw, Gregory Robinson, and Arthur M. Mercurio
The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis, Robin E. Bachelder, Melissa A. Wendt, Naoya Fujita, Takashi Tsuruo, and Arthur M. Mercurio
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function, Sharon B. Cantor, Daphne W. Bell, Shridar Ganesan, Elizabeth M. Kass, Ronny Drapkin, Steven R. Grossman, Doke C. R. Wahrer, Dennis C. Sgroi, William S. Lane, Daniel A. Haber, and David M. Livingston
Integrin laminin receptors and breast carcinoma progression, Arthur M. Mercurio, Robin E. Bachelder, Jun Chung, Kathleen L. O'Connor, Isaac Rabinovitz, Leslie M. Shaw, and Taneli Tani
Towards a mechanistic understanding of tumor invasion--lessons from the alpha6beta 4 integrin, Arthur M. Mercurio and Isaac Rabinovitz
The alpha 6 beta 4 integrin and epithelial cell migration, Arthur M. Mercurio, Isaac Rabinovitz, and Leslie M. Shaw
Protein kinase A regulates Rac and is required for the growth factor-stimulated migration of carcinoma cells, Kathleen L. O'Connor and Arthur M. Mercurio
Traction forces mediated by alpha6beta4 integrin: implications for basement membrane organization and tumor invasion, Isaac Rabinovitz, I. K. Gipson, and Arthur M. Mercurio
PDZ interaction sites in integrin alpha subunits. T14853, TIP/GIPC binds to a type I recognition sequence in alpha 6A/alpha 5 and a novel sequence in alpha 6B, Taneli Tani and Arthur M. Mercurio
Publications from 2000
Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion, Daniela Gambaletta, Alessandra Marchetti, Laura Benedetti, Arthur M. Mercurio, Ada Sacchi, and Rita Falcioni
Intestinal restitution: progression of actin cytoskeleton rearrangements and integrin function in a model of epithelial wound healing, Margaret M. Lotz, Isaac Rabinovitz, and Arthur M. Mercurio
RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism, Kathleen L. O'Connor, B. K. Nguyen, and Arthur M. Mercurio
Publications from 1999
Activation of p53 function in carcinoma cells by the alpha6beta4 integrin, Robin E. Bachelder, Alessandra Marchetti, Rita Falcioni, Silvia Soddu, and Arthur M. Mercurio
p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB, Robin E. Bachelder, Mark J. Ribick, Alessandra Marchetti, Rita Falcioni, Silvia Soddu, Kathryn R. Davis, and Arthur M. Mercurio
BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway, Junjie Chen, Daniel P. Silver, Sharon B. Cantor, David M. Livingston, and Ralph Scully
Evidence that distinct states of the integrin alpha6beta1 interact with laminin and an ADAM, M. S. Chen, E. A. Almeida, A. P. Huovila, Y. Takahashi, Leslie M. Shaw, Arthur M. Mercurio, and J. M. White
Protein kinase C-dependent mobilization of the alpha6beta4 integrin from hemidesmosomes and its association with actin-rich cell protrusions drive the chemotactic migration of carcinoma cells, Isaac Rabinovitz, Alex Toker, and Arthur M. Mercurio
Publications from 1998
Knockout of alpha6 beta1-integrin expression reverses the transformed phenotype of hepatocarcinoma cells, Vinicio Carloni, Roberto G. Romanelli, Arthur M. Mercurio, Massimo Pinzani, Giacomo Laffi, Giorgio Cotrozzi, and Paolo Gentilini
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells, Junjie Chen, Daniel P. Silver, Deepika Walpita, Sharon B. Cantor, Adi F. Gazdar, Gail Tomlinson, Fergus J. Couch, Barbara L. Weber, Terry Ashley, David M. Livingston, and Ralph Scully
Endothelial cells assemble two distinct alpha6beta4-containing vimentin-associated structures: roles for ligand binding and the beta4 cytoplasmic tail, Suzanne M. Homan, Arthur M. Mercurio, and Susan E. LaFlamme
Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells, Kathleen L. O'Connor, Leslie M. Shaw, and Arthur M. Mercurio
The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of actin-containing motility structures, Isaac Rabinovitz and Arthur M. Mercurio
Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion, Leslie M. Shaw, Isaac Rabinovitz, Helen H. Wang, Alex Toker, and Arthur M. Mercurio
Regulation of mitogen-activated protein kinase activation by the cytoplasmic domain of the alpha6 integrin subunit, Jueyang Wei, Leslie M. Shaw, and Arthur M. Mercurio
Publications from 1997
Association between sucrase-isomaltase and p53 expression in colorectal cancer, Mario Lise, Massimo Loda, Michelangelo Fiorentino, Arthur M. Mercurio, Ian C. Summerhayes, Phillip T. Lavin, and J. Milburn Jessup
Intestinal epithelial restitution. Involvement of specific laminin isoforms and integrin laminin receptors in wound closure of a transformed model epithelium, Margaret M. Lotz, A. Nusrat, J. L. Madara, R. Ezzell, Ulla M. Wewer, and Arthur M. Mercurio
Integrin signaling in leukocytes: lessons from the alpha6beta1 integrin, Jueyang Wei, Leslie M. Shaw, and Arthur M. Mercurio
The integrin alpha 6 beta 1 promotes the survival of metastatic human breast carcinoma cells in mice, Ulla M. Wewer, Leslie M. Shaw, R. Albrechtsen, and Arthur M. Mercurio
Publications from 1996
A function for the integrin alpha6beta4 in the invasive properties of colorectal carcinoma cells, Celia Chao, Margaret M. Lotz, Andrew C. Clarke, and Arthur M. Mercurio
Evidence for a Ras/Ral signaling cascade, Larry A. Feig, Takeshi Urano, and Sharon B. Cantor
The integrin alpha 6 beta 4 and the biology of carcinoma, Isaac Rabinovitz and Arthur M. Mercurio
Function of the integrin alpha 6 beta 1 in metastatic breast carcinoma cells assessed by expression of a dominant-negative receptor, Leslie M. Shaw, Celia Chao, Ulla M. Wewer, and Arthur M. Mercurio
Publications from 1995
Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor, Eduardo A. C. Almeida, A. P.J. Huovila, A. E. Sutherland, L. E. Stephens, P. G. Calarco, Leslie M. Shaw, Arthur M. Mercurio, A. Sonnenberg, P. Primakoff, D. G. Myles, and J. M. White
Role of the E-cadherin/alpha-catenin complex in modulating cell-cell and cell-matrix adhesive properties of invasive colon carcinoma cells, Ellen C. Breen, Glenn D. Steele Jr., and Arthur M. Mercurio
Role of E-cadherin in the response of tumor cell aggregates to lymphatic, venous and arterial flow: measurement of cell-cell adhesion strength, Stephen W. Byers, Connie L. Sommers, Becky Hoxter, Arthur M. Mercurio, and Aydin Tozeren
Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases, Sharon B. Cantor, Takeshi Urano, and Larry A. Feig
Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain, Astrid S. Clark, Margaret M. Lotz, Celia Chao, and Arthur M. Mercurio
Sucrase-isomaltase is an independent prognostic marker for colorectal carcinoma, J. Milburn Jessup, Phillip T. Lavin, Charles W. Andrews Jr., Massimo Loda, Arthur M. Mercurio, B. D. Minsky, C. Mies, B. Cukor, R. Bleday, and Glenn D. Steele Jr.
Laminin receptors: achieving specificity through cooperation, Arthur M. Mercurio
The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins, Leslie M. Shaw, Christopher E. Turner, and Arthur M. Mercurio
E-selectin-mediated dynamic interactions of breast- and colon-cancer cells with endothelial-cell monolayers, Aydin Tozeren, Hynda K. Kleinman, Derrick S. Grant, David Morales, Arthur M. Mercurio, and Stephen W. Byers
Publications from 1994
Regulation of cellular interactions with laminin by integrin cytoplasmic domains: the A and B structural variants of the alpha 6 beta 1 integrin differentially modulate the adhesive strength, morphology, and migration of macrophages, Leslie M. Shaw and Arthur M. Mercurio
Integrin alpha 6 beta 4 mediates dynamic interactions with laminin, Aydin Tozeren, Hynda K. Kleinman, Stephen Wu, Arthur M. Mercurio, and Stephen W. Byers
Publications from 1993
Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma, Margaret M. Lotz, Charles W. Andrews Jr., Cynthia A. Korzelius, Edward C. Lee, Glenn D. Steele Jr., Astrid Clarke, and Arthur M. Mercurio
Fimbrin localized to an insoluble cytoskeletal fraction is constitutively phosphorylated on its headpiece domain in adherent macrophages, Jeanne M. Messier, Leslie M. Shaw, M. Chafel, Paul Matsudaira, and Arthur M. Mercurio
Inside-out integrin signaling in macrophages. Analysis of the role of the alpha 6A beta 1 and alpha 6B beta 1 integrin variants in laminin adhesion by cDNA expression in an alpha 6 integrin-deficient macrophage cell line, Leslie M. Shaw, Margaret M. Lotz, and Arthur M. Mercurio
Regulation of alpha 6 beta 1 integrin laminin receptor function by the cytoplasmic domain of the alpha 6 subunit, Leslie M. Shaw and Arthur M. Mercurio
Publications from 1992
Sucrase-isomaltase expression in chronic ulcerative colitis and dysplasia, Charles W. Andrews Jr., Carl J. O'Hara, Harvey Goldman, Arthur M. Mercurio, Mark L. Silverman, and Glenn D. Steele Jr.
The integrin alpha 6 beta 4 is a laminin receptor, Edward C. Lee, Margaret M. Lotz, Glenn D. Steele Jr., and Arthur M. Mercurio
Publications from 1991
Carbohydrate-binding protein 35 is the major cell-surface laminin-binding protein in colon carcinoma, Edward C. Lee, Hee-Jong Woo, Cynthia A. Korzelius, Glenn D. Steele Jr., and Arthur M. Mercurio
Laminin binding proteins, Arthur M. Mercurio and Leslie M. Shaw
Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186, Hee-Jong Woo, Margaret M. Lotz, Jae U. Jung, and Arthur M. Mercurio
Publications from 1990
Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins, Margaret M. Lotz, Cynthia A. Korzelius, and Arthur M. Mercurio
Laminin: multiple forms, multiple receptors, Arthur M. Mercurio
The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin, Leslie M. Shaw, Jeanne M. Messier, and Arthur M. Mercurio
The major non-integrin laminin binding protein of macrophages is identical to carbohydrate binding protein 35 (Mac-2), Hee-Jong Woo, Leslie M. Shaw, Jeanne M. Messier, and Arthur M. Mercurio
Publications from 1989
Relationship between extracellular matrix interactions and degree of differentiation in human colon carcinoma cell lines, George W. Daneker Jr., Andrea J. Piazza, Glenn D. Steele Jr., and Arthur M. Mercurio
Interferon gamma and lipopolysaccharide promote macrophage adherence to basement membrane glycoproteins, Leslie M. Shaw and Arthur M. Mercurio
Publications from 1988
Macrophage interactions with laminin: PMA selectively induces the adherence and spreading of mouse macrophages on a laminin substratum, Arthur M. Mercurio and Leslie M. Shaw
Publications from 1987
Laminin expression in colorectal carcinomas varying in degree of differentiation, George W. Daneker Jr., Arthur M. Mercurio, Lisa Guerra, Barbara Wolf, Ronald R. Salem, Darius J. Bagli, and Glenn D. Steele Jr.
Modulation of two distinct galactosyltransferase activities in populations of mouse peritoneal macrophages, Bradley T. Sheares and Arthur M. Mercurio
Publications from 1986
Disruption of oligosaccharide processing in murine tumor cells inhibits their susceptibility to lysis by activated mouse macrophages, Arthur M. Mercurio
Publications from 1985
Activation of mouse peritoneal macrophages alters the structure and surface expression of protein-bound lactosaminoglycans, Arthur M. Mercurio and Phillips W. Robbins
Publications from 1984
Glycolipids of the mouse peritoneal macrophage. Alterations in amount and surface exposure of specific glycolipid species occur in response to inflammation and tumoricidal activation, Arthur M. Mercurio, Gerald A. Schwarting, and Phillips W. Robbins
Publications from 1982
Smooth endoplasmic reticulum and other agranular reticulum in frog retinal photoreceptors, Arthur M. Mercurio and Eric Holtzman
Ultrastructural localization of glycerolipid synthesis in rod cells of the isolated frog retina, Arthur M. Mercurio and Eric Holtzman
Publications from 1980
Membrane circulation in neurons and photoreceptors: some unresolved issues, Eric Holtzman and Arthur M. Mercurio
