Title

Laminin binding proteins

UMMS Affiliation

Department of Cancer Biology

Date

9-1-1991

Document Type

Article

Subjects

Animals; Cytosol; Integrins; Laminin; Lectins; Neoplasm Proteins; Receptors, Immunologic; Receptors, Laminin; Signal Transduction

Abstract

Cells express many proteins that bind to laminin, the major adhesive component of basement membranes. Some of these, specifically integrins, function as transmembrane receptors that 'signal' the presence of laminin on the cell surface to the cytoplasm. Lectins constitute a second class of laminin binding proteins that may augment integrin function by interacting with laminin carbohydrate. Caution must be used in ascribing functions to other laminin binding proteins, especially cytosolic proteins.

Rights and Permissions

Citation: Bioessays. 1991 Sep;13(9):469-73. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

1839124