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This chapter in Cancer Concepts: A Guidebook for the Non-Oncologist presents a summary of the most relevant causative agents of cancer. Exposure to many environmental agents is associated with an increased incidence of certain malignancies, although causation is usually difficult to prove. Certain chemicals, infections (parasitic, viral, and bacterial) and ionizing radiation are known carcinogens. Variable genetic susceptibility to carcinogenesis is apparent. Up to 2/3 of human cancers are believed to have an environmental component.
University of Massachusetts Medical School
carcinogenesis, carcinogens, environmental factors, infectious agents, radiation, malignancy, cancer
Cancer Biology | Environmental Public Health | Neoplasms | Oncology
Peters ML, Pieters RS, Liebmann J. Environmental and Infectious Causes of Malignancy. In: Pieters RS, Liebmann J, eds. Cancer Concepts: A Guidebook for the Non-Oncologist. 2nd ed. Worcester, MA: University of Massachusetts Medical School; 2015. doi:10.7191/cancer_concepts.1007.
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