http://dx.doi.org/10.7191/cancer_concepts.1001">
 

Files

Download

Download Full Text (336 KB)

Description

While the majority of cancers are not inherited, there are a number of well described collections of cancers that occur within families. These cancer syndromes were initially identified based on observation of the family history and subsequently the molecular mechanisms have been elucidated. This chapter in Cancer Concepts: A Guidebook for the Non-Oncologist is intended to allow the reader to recognize when a pattern of cancers occurs in an individual or their family, and to generate an investigation into potential cancer syndromes. With the rapidly expanding understanding of the molecular basis of cancers at the cellular and constitutional levels, appropriate preventive care may be offered and tailored treatment holds great promise.

Publication Date

9-13-2011

Publisher

University of Massachusetts Medical School

City

Worcester, MA

Keywords

Early onset cancer, genetic risk, Knudson’s hypothesis, mutations

Disciplines

Cancer Biology | Neoplasms | Oncology

 

Creative Commons

This work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License