Title

Growth-rate-dependent transcription initiation from the dam P2 promoter

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology

Date

5-19-1995

Document Type

Article

Medical Subject Headings

Base Sequence; Colon; Escherichia coli; Escherichia coli Proteins; *Gene Expression Regulation, Bacterial; Humans; Methyltransferases; *Promoter Regions, Genetic; Recombinant Fusion Proteins; *Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; beta-Galactosidase

Abstract

Transcription of the dam gene in Escherichia coli is dependent on growth rate. Using single-copy promoter::lacZYA fusions we found that of the five promoter regions which affect dam expression, only the P2 promoter shows growth-rate dependence. The determinants for growth-rate control must lie in the region -52 to +27 relative to the transcription start point.

Rights and Permissions

Citation: Gene. 1995 May 19;157(1-2):213-5.

Related Resources

Link to Article in PubMed

PubMed ID

7607492