Growth-rate-dependent transcription initiation from the dam P2 promoter
Department of Biochemistry and Molecular Pharmacology
Medical Subject Headings
Base Sequence; Colon; Escherichia coli; Escherichia coli Proteins; *Gene Expression Regulation, Bacterial; Humans; Methyltransferases; *Promoter Regions, Genetic; Recombinant Fusion Proteins; *Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; beta-Galactosidase
Transcription of the dam gene in Escherichia coli is dependent on growth rate. Using single-copy promoter::lacZYA fusions we found that of the five promoter regions which affect dam expression, only the P2 promoter shows growth-rate dependence. The determinants for growth-rate control must lie in the region -52 to +27 relative to the transcription start point.
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Citation: Gene. 1995 May 19;157(1-2):213-5.
Rasmussen, Lene Juel; Lobner-Olesen, Anders; and Marinus, Martin G., "Growth-rate-dependent transcription initiation from the dam P2 promoter" (1995). Biochemistry and Molecular Pharmacology Publications and Presentations. Paper 45.