Title

Single-molecule tracking in eukaryotic cell nuclei

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology; RNA Therapeutics Institute

Date

1-2007

Document Type

Article

Medical Subject Headings

Carbocyanines; Cell Nucleus; Green Fluorescent Proteins; HeLa Cells; Humans; Microscopy, Fluorescence; Nuclear Proteins; RNA-Binding Proteins; Recombinant Fusion Proteins; Ribonucleoprotein, U1 Small Nuclear; Transfection

Abstract

Visualization of single fluorescent molecules (single-molecule tracking, SMT) within cells provides a real-time molecular view of physiological processes in vivo.

Comments

Citation: Siebrasse JP, Grünwald D, Kubitscheck U. Single-molecule tracking in eukaryotic cell nuclei. Anal Bioanal Chem. 2007 Jan;387(1):41-4. doi:10.1007/s00216-006-0763-0.

At the time of publication, David Grünwald was not yet affiliated with the University of Massachusetts Medical School.

Related Resources

Link to Article in PubMed