Title

Small RNA-Directed Silencing: The Fly Finds Its Inner Fission Yeast

UMMS Affiliation

Department of Biochemistry and Molecular Pharmacology

Date

4-22-2013

Document Type

Article

Medical Subject Headings

RNA, Small Interfering

Abstract

Several recent studies demonstrate that piRNAs guide Piwi protein to repress transposon transcription in fly ovaries, much as fission yeast use siRNAs to silence repeat sequences. Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the specialized heterochromatic loci that produce piRNA precursors.

Rights and Permissions

Citation: Curr Biol. 2013 Apr 22;23(8):R318-20. doi: 10.1016/j.cub.2013.03.033. Link to article on publisher's site

Related Resources

Link to Article in PubMed

PubMed ID

23618667