UMass Chan Affiliations
Department of Biochemistry and Molecular PharmacologyProgram in Bioinformatics and Integrative Biology
Document Type
Journal ArticlePublication Date
2016-01-03
Metadata
Show full item recordAbstract
Rapid development and commercialization of instruments that can accurately, rapidly, and cheaply sequence billions of DNA bases is revolutionizing molecular biology and medicine. Because a reference genome is usually available, the first bioinformatics challenge presented by the new generation of high-throughput sequencers is the genome mapping problem, where each read is mapped to a reference genome to reveal its location(s). An introduction to mapping algorithms, as well as factors that influence their results, is provided here.Source
Cold Spring Harb Protoc. 2017 Jan 3;2017(1):pdb.top093153. doi: 10.1101/pdb.top093153. Link to article on publisher's siteDOI
10.1101/pdb.top093153Permanent Link to this Item
http://hdl.handle.net/20.500.14038/25950PubMed ID
27574203Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1101/pdb.top093153