Comparison of the duration of antimicrobial activity of 2 different antimicrobial central venous catheters
Department of Anesthesiology; Department of Surgery
Medical Subject Headings
Anti-Infective Agents; Bacterial Adhesion; Catheterization, Central Venous; Catheters, Indwelling; Gram-Positive Bacteria; Massachusetts; Minocycline; Rifampin
We compared the duration of antimicrobial effectiveness of 2 different antimicrobial catheters. The baseline activity of minocycline-rifampin catheters was greater than that of silver-platinum-carbon catheters against Staphylococcus aureus, Staphylococcus epidermidis, and Enterococcus faecalis. The antimicrobial activity of the minocycline-rifampin catheters against these pathogens persisted for up to 12 days, while that of the silver-platinum-carbon catheters was depleted by day 10 (P < .05).
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Citation: Infect Control Hosp Epidemiol. 2010 Mar;31(3):295-7. Link to article on publisher's site
Matheos, Theofilos; Walz, J. Matthias; Adams, Janice P.; Johnson, Karen; Longtine, Karen J.; Longtine, Jaclyn K.; O'Neill, Melissa A.; and Heard, Stephen O., "Comparison of the duration of antimicrobial activity of 2 different antimicrobial central venous catheters" (2010). Anesthesiology Publications and Presentations. Paper 24.