Department of Anesthesiology
Medical Subject Headings
Thrombocytopenia; Anti-Bacterial Agents
Thrombocytopenia is the most common coagulation problem in ICU patients and is an independent predictor of death among critically ill patients. The differential diagnosis of acute thrombocytopenia in an ICU patient is extensive. After eliminating the more common etiologies, drug-induced thrombocytopenia (DITP) should be considered as an often overlooked yet easily reversible cause of thrombocytopenia. Due to a lack of distinguishing clinical features and numerous other possible etiologies, diagnosis is often complex, requiring a multi-step approach. We discuss the extensive workup of DITP in the context of this unusual case presentation.
Khoury, Spiro and Watson, Nicholas C., "Antibiotic-Induced Thrombocytopenia in the ICU: Case Report of a Diagnostic Challenge" (2012). Anesthesiology and Perioperative Medicine Publications. 116.